ArticleRespiratory medicine case reports2021
Immune-related adverse events caused by treatment with pembrolizumab in a patient with lung cancer who infected influenza virus.
Article in Respiratory medicine case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Myocardial immune vulnerability unmasked after treatment with immune checkpoint inhibitors: a case report.European heart journal. Case reports · 2026Article
- Development and Validation of a Nomogram to Predict Respiratory Failure With Influenza.Immunity, inflammation and disease · 2026Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
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Abstract
A 67-year-old man with stage IV B lung adenocarcinoma was treated with pembrolizumab. The patient was admitted to the hospital because of influenza on the day of the second cycle of pembrolizumab treatment. He was diagnosed with pneumonia and was treated with antiviral drugs and steroids. However, the patient eventually died. In this case, treatment with immune checkpoint inhibitors might have affected the immune response caused by influenza virus infection, that might have caused lung injury, which is an immune-related adverse event (irAE). Hence, it is important that, caution should be taken to prevent transmission of viral infection, and Therefore, it is important to prevent viral infections, but caution should also be paid to the possibility that infections may cause irAEs in patients with lung cancer.
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