ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
Understanding Surface Modifications Induced via Argon Plasma Treatment through Secondary Electron Hyperspectral Imaging.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Secondary Electron Hyperspectral Imaging (SEHI) in FIB - SEM for Proton Exchange Membrane Fuel Cells Technology.ACS omega · 2026Article
- Secondary Electron Hyperspectral Imaging of Carbons: New Insights and Good Practice Guide.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Article
- Synthesis, Morphology, and Biomedical Applications of Plasma-Based Polymers: Recent Trends and Advances.Polymers · 2024Review
- Revealing The Morphology of Ink and Aerosol Jet Printed Palladium-Silver Alloys Fabricated from Metal Organic Decomposition Inks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Plasma Modification Techniques for Natural Polymer-Based Drug Delivery Systems.Pharmaceutics · 2023Review
- Article
- Characterization in respect to degradation of titanium-coated polypropylene surgical mesh explanted from humans.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Development of PCL PolyHIPE Substrates for 3D Breast Cancer Cell Culture.Bioengineering (Basel, Switzerland) · 2023Article
- Biological Risk Assessment of Three Dental Composite Materials following Gas Plasma Exposure.Molecules (Basel, Switzerland) · 2022Article
- Revealing Localised Mechanochemistry of Biomaterials UsingMaterials (Basel, Switzerland) · 2022Article
- A novel characterisation approach to reveal the mechano-chemical effects of oxidation and dynamic distension on polypropylene surgical mesh.RSC advances · 2021Article
- Monitoring Carbon in Electron and Ion Beam Deposition within FIB-SEM.Materials (Basel, Switzerland) · 2021Article
- Understanding Surface Modifications Induced via Argon Plasma Treatment through Secondary Electron Hyperspectral Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the effects that sterilization methods have on the surface of a biomaterial is a prerequisite for clinical deployment. Sterilization causes alterations in a material's surface chemistry and surface structures that can result in significant changes to its cellular response. Here we compare surfaces resulting from the application of the industry standard autoclave sterilisation to that of surfaces resulting from the use of low-pressure Argon glow discharge within a novel gas permeable packaging method in order to explore a potential new biomaterial sterilisation method. Material surfaces are assessed by applying secondary electron hyperspectral imaging (SEHI). SEHI is a novel low-voltage scanning electron microscopy based characterization technique that, in addition to capturing topographical images, also provides nanoscale resolution chemical maps by utilizing the energy distribution of emitted secondary electrons. Here, SEHI maps are exploited to assess the lateral distributions of diverse functional groups that are effected by the sterilization treatments. This information combined with a range of conventional surface analysis techniques and a cellular metabolic activity assay reveals persuasive reasons as to why low-pressure argon glow discharge should be considered for further optimization as a potential terminal sterilization method for PGS-M, a functionalized form of poly(glycerol sebacate) (PGS).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.