Evidence map›Paper›PMID 33643762›Full record

Article3 Biotech2021

Cordifolioside: potent inhibitor against M

Munikumar Manne, Giridhar Goudar, Seshadri Reddy Varikasuvu, Mahadev C Khetagoudar, Hema Kanipakam, Pradeep Natarajan, Muni Divya Ummiti, Vijay Aravind Yenagi, Sridhar Chinthakindi, Prakash Dharani and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review:Open life sciences · 2024
    Review
  5. Review
  6. RSC advances · 2022
    Article
  7. Article
  8. Inhibition of the main protease of SARS-CoV-2 (MComputational and structural biotechnology journal · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Munikumar ManneNutrition Information, Communication & Health Education (NICHE), ICMR-National Institute of Nutrition, Hyderabad, Telangana India.ORCID 0000-0003-1838-122X
Giridhar Goudar *Food Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Seshadri Reddy VarikasuvuDepartment of Biochemistry, All India Institute of Medical Sciences, Deoghar, Jharkhand India.
Mahadev C KhetagoudarFood Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Hema KanipakamDBT-BioCARe, Translational Bioinformatics-TBG, International Centre for Genetic Engineering and Biotechnology (ICGEB), Aruna Asaf Ali Marg, New Delhi, India.
Pradeep NatarajanDepartment of Biotechnology and Medical Engineering, BIF Centre, National Institute of Technology (NIT), Rourkela, Odisha India.
Muni Divya UmmitiFood Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Vijay Aravind YenagiMulti-Disciplinary Research Unit, DIMHANS, Dharwad, Karnataka India.
Sridhar ChinthakindiDepartment of Environmental Medicine, New York University School of Medicine, New York, NY USA.
Prakash DharaniWater Testing Laboratory, BWSSB, Bangalore, Karnataka India.
Durga Sai Sri ThotaFood Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Sameer PatilFood Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Vijaylaxmi PatilFood Quality Analysis and Biochemistry Division, Biochem Research and Testing Laboratory, Dharwad, Karnataka India.
Analysis and Testing Centre · CNAll India Institute of Medical Sciences, Deoghar · INBangalore Diabetes Centre · INCentre for Multi-disciplinary Development Research · INInternational Centre for Genetic Engineering and Biotechnology · INNational Institute of Nutrition · INNational Institute of Technology Rourkela · INNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic options for SARS-CoV-2 are limited merely to the symptoms or repurposed drugs and non-specific interventions to promote the human immune system. In the present study, chromatographic and in silico approaches were implemented to identify bioactive compounds which might play pivotal role as inhibitor for SARS-CoV-2 and human immunomodulator (TGF-β and TNF-α).

Indexed as

COVID-19Dynamics simulationsHPTLCMain proteaseMolecular dockingSARS-CoV-2Sequence analysisTinospora cordifolia

Identifiers

PMID33643762
PMCPMC7898013
OpenAlexW3132196538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.