Evidence map›Paper›PMID 33643737›Full record

ArticleCureus2021

Steroid-Induced Hiccups in a Patient Managed for Pseudo Foster-Kennedy Syndrome: A Case Report of Good Outcome With the use of Gabapentin.

Ejike Egbu, Chidi Ihemedu, Ugochukwu A Eze, Chukwuemeka Nwajei, Morgan Ikponmwosa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ejike EgbuOphthalmology, Lily Hospitals Limited, Warri, NGA.
Chidi IhemeduOphthalmology, Lily Hospitals Limited, Warri, NGA.
Ugochukwu A EzeOphthalmology, Katsina Eye Center, Katsina, NGA.
Chukwuemeka NwajeiOphthalmology, Central Hospital, Sapele, NGA.
Morgan IkponmwosaRadiology, Lily Hospitals Limited, Warri, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of IV methylprednisolone has been shown to be associated with some adverse effects. The most feared side effect is acute gastrointestinal perforation and accelerated hypertension particularly during pulse therapy. Hiccups occur less frequently but can cause high levels of discomfort to the patient. In intractable cases, respiratory arrest and death can occur. This article reports the occurrence of hiccups in a patient managed for pseudo Foster-Kennedy syndrome. The hiccups were observed shortly after IV methylprednisolone was administered to the patient and abetted over a period of one week after it was discontinued. Hiccups occur through the neuronal pathway of the hiccup reflex arc, comprising the vagus nerve, phrenic nerve, parts of the sympathetic nervous system (T6-T12), and efferent fibers from the phrenic nerve that supply the glottis and the accessory muscles of respiration. The hiccups resolved with the use of gabapentin. This case report aims to add to the existing body of knowledge of the efficacy of gabapentin in the management of hiccups.

Indexed as

a case of pseudo foster kennedy syndromechlorpromazinegabapentin as treatment for hiccupsmanagement of optic neuritis in a patient with diabetesmechanism and pathway for hiccupsmethylprednisolonepseudo foster-kennedy syndromesteroids induced hiccups

Identifiers

PMID33643737
PMCPMC7903257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.