Evidence map›Paper›PMID 33643378›Full record

ArticleFrontiers in genetics2021

Comparison of Gene Editing Versus Conventional Breeding to Introgress the

Maci L Mueller, John B Cole, Natalie K Connors, David J Johnston, Imtiaz A S Randhawa, Alison L Van Eenennaam

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  3. Review
  4. Welfare of beef cattle.EFSA journal. European Food Safety Authority · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Maci L MuellerDepartment of Animal Science, University of California, Davis, Davis, CA, United States.
John B ColeAnimal Genomics and Improvement Laboratory, Agricultural Research Service, United States Department of Agricultural, Beltsville, MD, United States.
Natalie K ConnorsAnimal Genetics and Breeding Unit (AGBU), University of New England, Armidale, NSW, Australia.
David J JohnstonAnimal Genetics and Breeding Unit (AGBU), University of New England, Armidale, NSW, Australia.
Imtiaz A S RandhawaSchool of Veterinary Science, The University of Queensland, Gatton, QLD, Australia.
Alison L Van EenennaamDepartment of Animal Science, University of California, Davis, Davis, CA, United States.
University of California, Davis · USUniversity of New England · AUAgricultural Research Service · USUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehorning is the process of physically removing horns to protect animals and humans from injury, but the process is costly, unpleasant, and faces increasing public scrutiny. Genetic selection for polled (hornless), which is genetically dominant to horned, is a long-term solution to eliminate the need for dehorning. However, due to the limited number of polled Australian Brahman bulls, the northern Australian beef cattle population remains predominantly horned. The potential to use gene editing to produce high-genetic-merit polled cattle was recently demonstrated. To further explore the concept, this study simulated introgression of the

Indexed as

Australiabeef cattleBrahmangene editingpolledsimulation

Identifiers

PMID33643378
PMCPMC7905321
OpenAlexW2990902748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.