Evidence map›Paper›PMID 33643311›Full record

ArticleFrontiers in immunology2021

Tissue-Specificity of Antibodies Raised Against TrkB and p75

Samuel Fleury, Imane Boukhatem, Jessica Le Blanc, Mélanie Welman, Marie Lordkipanidzé

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. The intriguing role of platelets as custodians of brain-derived neurotrophic factor.Research and practice in thrombosis and haemostasis · 2024
    Article
  4. Article
  5. Illustrated State-of-the-Art Capsules of the ISTH 2023 Congress.Research and practice in thrombosis and haemostasis · 2023
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel FleuryResearch Center, Montreal Heart Institute, Montreal, QC, Canada.
Imane BoukhatemResearch Center, Montreal Heart Institute, Montreal, QC, Canada.
Jessica Le BlancResearch Center, Montreal Heart Institute, Montreal, QC, Canada.
Mélanie WelmanResearch Center, Montreal Heart Institute, Montreal, QC, Canada.
Marie LordkipanidzéResearch Center, Montreal Heart Institute, Montreal, QC, Canada.
Montreal Heart Institute · CAUniversité de Montréal · CA

Funding

CIHR PJT-159569
6 · The paper itself

Abstract

Platelets and neurons share many similarities including comparable secretory granule types with homologous calcium-dependent secretory mechanisms as well as internalization, sequestration and secretion of many neurotransmitters. Thus, platelets present a high potential to be used as peripheral biomarkers to reflect neuronal pathologies. The brain-derived neurotrophic factor (BDNF) acts as a neuronal growth factor involved in learning and memory through the binding of two receptors, the tropomyosin receptor kinase B (TrkB) and the 75 kDa pan-neurotrophic receptor (p75

Indexed as

Antibody SpecificityAutoantibodiesAutoantigensBiomarkersBlood PlateletsBrain-Derived Neurotrophic FactorCell LineGlycosylationHumansMembrane GlycoproteinsNerve Tissue ProteinsNeurodegenerative DiseasesNeuronsProtein TransportReceptors, Nerve Growth FactorReceptor, trkBAutoantibodiesAutoantigensBDNF protein, humanBiomarkersBrain-Derived Neurotrophic FactorMembrane GlycoproteinsNerve Tissue ProteinsNGFR protein, humanReceptors, Nerve Growth FactorReceptor, trkBtropomyosin-related kinase-B, humanbrain-derived neurotrophic factorneurotrophin receptorspan-neurotrophic receptor p75NTRplatelettropomyosin receptor kinase B

Identifiers

PMID33643311
PMCPMC7905091
OpenAlexW3130507619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.