Evidence map›Paper›PMID 33643303›Full record

ArticleFrontiers in immunology2020

IgE and T Cell Reactivity to a Comprehensive Panel of Cockroach Allergens in Relation to Disease.

Anna Pomés, Véronique Schulten, Jill Glesner, Ricardo da Silva Antunes, Aaron Sutherland, Leonard B Bacharier, Avraham Beigelman, Paula Busse, April Frazier, Alessandro Sette

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Anna PomésBasic Research, Indoor Biotechnologies, Inc., Charlottesville, VA, United States.
Véronique SchultenCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.
Jill GlesnerBasic Research, Indoor Biotechnologies, Inc., Charlottesville, VA, United States.
Ricardo da Silva AntunesCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.
Aaron SutherlandCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.
Leonard B BacharierDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Avraham BeigelmanDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, United States.
Paula BusseDivision of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
April FrazierCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, United States.
La Jolla Institute for Immunology · USIndoor Biotechnologies (United States) · USWashington University in St. Louis · USIcahn School of Medicine at Mount Sinai · US

Funding

Antigenic determinants of asthma-associated allergens for design of immunotherapy.R01AI077653 · NIAID · INDOOR BIOTECHNOLOGIES · PI MARTIN D. CHAPMAN, Maksymilian Chruszcz · 2009 to 2026
$9.5M
NIAID NIH HHS R01 AI077653
6 · The paper itself

Abstract

IgE sensitization to cockroach allergens is associated with development of allergic diseases, such as asthma. To understand the relevance of different cockroach allergens for diagnosis and immunotherapy, a comprehensive analysis of IgE antibody levels and T cell reactivity to an expanded set of cockroach allergens and their relationship to disease was performed in a cohort of USA cockroach sensitized patients. IgE antibody levels to recombinant chitinase and hemocyanin were measured for 23 subjects by custom-made ImmunoCAPs and compared with IgE levels to eight cockroach allergens we previously reported for the same cohort.

Indexed as

BlattellidaeAdultAllergensAnimalsFemaleHumansHypersensitivityImmunoglobulin EInsect ProteinsMaleMiddle AgedT-LymphocytesAllergensBla g 3 allergen; Periplaneta americanaImmunoglobulin EInsect Proteinsasthmacockroach allergydiagnosisIgEimmunotherapyrhinitisT-cell reactivity

Identifiers

PMID33643303
PMCPMC7902920
OpenAlexW3127235383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.