ArticleFrontiers in physiology2020
Association Between Intermittent Hypoxia and Left Ventricular Remodeling in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- PANoptosis links gut dysbiosis to obstructive sleep apnea-associated atherosclerosis: a gut-vascular inflammatory axis.Frontiers in immunology · 2026Review
- A composite score of polygraphic oximetry parameters predicts left ventricular hypertrophy in patients with obstructive sleep apnoea.ERJ open research · 2025Article
- Chronic intermittent hypoxia exacerbates isoproterenol-induced cardiac hypertrophy and apoptosis.Frontiers in cardiovascular medicine · 2025Article
- Association between obstructive sleep apnea and arrhythmia and heart rate variability among hypertensive patients.BMC cardiovascular disorders · 2024Article
- Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study.Lipids in health and disease · 2024Article
- Effects of obstructive sleep apnea on myocardial injury and dysfunction: a review focused on the molecular mechanisms of intermittent hypoxia.Sleep & breathing = Schlaf & Atmung · 2024Review
- Analysis of QRS complex morphology in children and adolescents with obstructive sleep apnea syndrome.European journal of pediatrics · 2024Article
- Interaction of estradiol and renin-angiotensin system with microRNAs-21 and -29 in renal fibrosis: focus on TGF-β/smad signaling pathway.Molecular biology reports · 2024Review
- Identification of key genes in chronic intermittent hypoxia-induced lung cancer progression based on transcriptome sequencing.BMC cancer · 2024Article
- Serum uric acid is related to left ventricular geometry and function in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Article
- Reversible cardiac function and left ventricular hypertrophy in a Chinese man with mitochondrial myopathy: a case report.BMC cardiovascular disorders · 2023Article
- Screening of plasma exosomal lncRNAs to identify potential biomarkers for obstructive sleep apnea.Annals of translational medicine · 2022Article
- Caloric restriction prevents obesity- and intermittent hypoxia-induced cardiac remodeling in leptin-deficientFrontiers in physiology · 2022Article
- Left Ventricular Mass, Geometric Patterns, and Diastolic Myocardial Performance in Children with Obstructive Sleep Apnea.Heart views : the official journal of the Gulf Heart AssociationArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was undertaken to examine the association between intermittent hypoxia and left ventricular (LV) remodeling and explore which parameter of intermittent hypoxia is most relevant to LV remodeling in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Two hundred eighty six patients underwent polysomnographic examination were enrolled. Based on apnea-hypoxia index (AHI), patients were divided into no, mild, moderate and severe OSAHS groups. Between-group differences in LV remodeling and the association between parameters of intermittent hypoxia and LV remodeling was evaluated. Patients with severe OSAHS were more likely to have hypertension, and higher values of LV mass (LVM) and LVM index (LVMI). In univariate regression analysis, male, body mass index (BMI), systolic and diastolic blood pressure (BP), statins, antihypertensive drugs, creatinine, and parameters of intermittent hypoxia (AHI, obstructive apnea index [OAI], lowest oxygen saturation [LSpO
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