Evidence map›Paper›PMID 33643050›Full record

ArticleFrontiers in pharmacology2021

Identification and Enzymatic Activity Evaluation of a Novel

Xiao-Yang Zhou, Xiang-Ran Lu, Ying-Hui Li, Ya-Qing Ma, Shi-Wen Zhao, Fang Wang, Ren-Ai Xu, Guo-Xin Hu, Jian-Ping Cai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Several antiplatelet gene SNPs, their haplotypes andFrontiers in cardiovascular medicine · 2026
    Article
  2. Role of Cytochrome P450 2C9 in COVID-19 Treatment: Current Status and Future Directions.European journal of drug metabolism and pharmacokinetics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xiao-Yang ZhouThe Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Beijing, China.
Xiang-Ran LuSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China.
Ying-Hui LiSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China.
Ya-Qing MaThe Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Beijing, China.
Shi-Wen ZhaoInstitute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Fang WangInstitute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Ren-Ai XuDepartment of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Guo-Xin HuSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China.
Jian-Ping CaiThe Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Beijing, China.
Wenzhou Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNBeijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Warfarin is a widely prescribed anticoagulant but the doses required to attain the optimum therapeutic effect exhibit dramatic inter-individual variability. Pharmacogenomics-guided warfarin dosing has been recommended to improve safety and effectiveness. We analyzed the cytochrome P450 2C9 (

Indexed as

allelic variantcytochrome P450 2C9drug metabolismenzymatic activity evaluation in vitrolosartantolbutamidewarfarin

Identifiers

PMID33643050
PMCPMC7905303
OpenAlexW3130189500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.