Evidence map›Paper›PMID 33643036›Full record

ArticleFrontiers in pharmacology2020

Protective Effect of Adenosine A

Ilaria Dettori, Lisa Gaviano, Filippo Ugolini, Daniele Lana, Irene Bulli, Giada Magni, Francesca Rossi, Maria Grazia Giovannini, Felicita Pedata

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. APurinergic signalling · 2025
    Review
  6. Article
  7. MRS3997, a dual adenosine ANeuropharmacology · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Blocking the AAnnals of medicine · 2022
    Article
  12. Article
  13. Selective block of adenosine ABritish journal of pharmacology · 2022
    Article
  14. Review
  15. Review
  16. Neuroprotective Effects of Cannabidiol but Not ΔInternational journal of molecular sciences · 2021
    Article
  17. Review
  18. AInternational journal of molecular sciences · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ilaria DettoriDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Division of Pharmacology and Toxicology, University of Florence, Florence, Italy.
Lisa GavianoDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Division of Pharmacology and Toxicology, University of Florence, Florence, Italy.
Filippo UgoliniDepartment of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.
Daniele LanaDepartment of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.
Irene BulliDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Division of Pharmacology and Toxicology, University of Florence, Florence, Italy.
Giada MagniInstitute of Applied Physics "Nello Carrara", National Research Council (IFAC-CNR), Florence, Italy.
Francesca RossiInstitute of Applied Physics "Nello Carrara", National Research Council (IFAC-CNR), Florence, Italy.
Maria Grazia GiovanniniDepartment of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.
Felicita PedataDepartment of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Division of Pharmacology and Toxicology, University of Florence, Florence, Italy.
University of Florence · ITNational Research Council · ITNello Carrara Institute of Applied Physics · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia. During ischemia, adenosine acts as an endogenous neuroprotectant. Few studies have investigated the role of A

Indexed as

adenosine A2B agonistblood biomarkerscerebral ischemiamiddle cerebral artery occlusionneuroinflammation

Identifiers

PMID33643036
PMCPMC7905306
OpenAlexW3128153901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.