Evidence map›Paper›PMID 33643020›Full record

ArticleFrontiers in aging neuroscience2021

Mild Motor Signs Matter in Typical Brain Aging: The Value of the UPDRS Score Within a Functionally Intact Cohort of Older Adults.

Jennifer Zitser, Kaitlin B Casaletto, Adam M Staffaroni, Claire Sexton, Sophia Weiner-Light, Amy Wolf, Jesse A Brown, Bruce L Miller, Joel H Kramer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: anNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Cortico-striatal functional connectivity and cerebral small vessel disease: Contribution to mild Parkinsonian signs.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jennifer ZitserMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Kaitlin B CasalettoMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Adam M StaffaroniMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Claire SextonMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Sophia Weiner-LightMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Amy WolfMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Jesse A BrownMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Bruce L MillerMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
Joel H KramerMemory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USUniversity Memory and Aging Center · USGlobal Brain Health Institute · USTel Aviv University · IL

Funding

PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, YADONG · 2004 to 2018
$27.1M
Mechanisms of Executive Decline in Normal AgingR01AG032289 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kaitlin B Casaletto, JOEL H KRAMER · 2009 to 2026
$8.3M
Effects of chronic inflammation on brain structure and functionR01AG048234 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRAMER, JOEL H · 2015 to 2019
$3.2M
Optimizing Clinical Trial Endpoints in Frontotemporal DementiaK23AG061253 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STAFFARONI, ADAM MARK · 2019 to 2023
$946k
Patient-tailored network prediction of neurodegenerative disease progressionK01AG055698 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BROWN, JESSE AARON · 2017 to 2022
$779k
NIA NIH HHS K01 AG055698NIA NIH HHS K23 AG061253NIA NIH HHS P50 AG023501NIA NIH HHS R01 AG032289NIA NIH HHS R01 AG048234
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingcognitionfMRImotor signsparkinsonismUPDRS

Identifiers

PMID33643020
PMCPMC7904682
OpenAlexW3128325854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.