ReviewFrontiers in neuroscience2021
The Neural Mechanisms of Tinnitus: A Perspective From Functional Magnetic Resonance Imaging.
Review in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of repetitive transcranial magnetic stimulation for subjective chronic tinnitus: a randomized controlled trial meta-analysis.Frontiers in neuroscience · 2025Pooled it
- Musical auditory training and cognitive auditory training: effects on the perception of tinnitus disorder.CoDAS · 2026Trial
- Hemodynamic Changes Following Acupuncture and Moxibustion in Patients with Subjective Tinnitus: An Acceleration Photoplethysmography and Pulsed-Wave Doppler Ultrasound Study.Audiology research · 2026Article
- Whole-Brain Structural Connectivity Alterations in Chronic Subjective Tinnitus: An Exploratory Diffusion Tensor Imaging Study.Brain sciences · 2026Article
- Article
- A large-scale, multi-site examination of resting state functional connectivity in tinnitus.Scientific reports · 2025Article
- Tinnitus and Cognition in the Elderly: Unraveling the Impact of Symptom Burden on Cognitive Decline.Brain sciences · 2025Article
- More than just noise: Association of pulsatile tinnitus with anxiety, depression, and reduction of quality of life.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Development and comparison of machine learning models for predicting moderate-to-severe tinnitus in patients with hearing loss.Frontiers in neurology · 2025Article
- Correlation of non-auditory comorbidities and hearing loss in chronic subjective tinnitus patients: a retrospective database study.Frontiers in neurology · 2025Article
- Unravelling the Silence: Exploring Tinnitus Pathophysiology and the Promise of Traditional Chinese Medicine.International journal of general medicine · 2025Review
- Tinnitus and dementia risk: a nationwide population-based case-control study.The Journal of laryngology and otology · 2024Article
- Thalamo-cortical neural mechanism of sodium salicylate-induced hyperacusis and anxiety-like behaviors.Communications biology · 2024Article
- Exploring the interplay of depression, sleep quality, and hearing in tinnitus-related handicap: insights from polysomnography and pure-tone audiometry.BMC psychiatry · 2024Article
- Amygdala structural and functional reorganization as an indicator of affective dysfunction in patients with tinnitus.Human brain mapping · 2024Article
- Tumor characteristics, brain functional activity, and connectivity of tinnitus in patients with vestibular schwannoma: a pilot study.Quantitative imaging in medicine and surgery · 2024Article
- Synergistic integration of Multi-View Brain Networks and advanced machine learning techniques for auditory disorders diagnostics.Brain informatics · 2024Article
- Association between tinnitus and hearing impairment among older adults with age-related hearing loss: a multi-center cross-sectional study.Frontiers in neurology · 2024Article
- Review
- Randomized controlled trial of a smartphone-based cognitive behavioral therapy for chronic tinnitus.PLOS digital health · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tinnitus refers to sound perception in the absence of external sound stimulus. It has become a worldwide problem affecting all age groups especially the elderly. Tinnitus often accompanies hearing loss and some mood disorders like depression and anxiety. The comprehensive adverse effects of tinnitus on people determine the severity of tinnitus. Understanding the mechanisms of tinnitus and related discomfort may be beneficial to the prevention and treatment, and then getting patients out of tinnitus distress. Functional magnetic resonance imaging (fMRI) is a powerful technique for characterizing the intrinsic brain activity and making us better understand the tinnitus neural mechanism. In this article, we review fMRI studies published in recent years on the neuroimaging mechanisms of tinnitus. The results have revealed various neural network alterations in tinnitus patients, including the auditory system, limbic system, default mode network, attention system, and some other areas involved in memory, emotion, attention, and control. Moreover, changes in functional connectivity and neural activity in these networks are related to the perception, persistence, and severity of tinnitus. In summary, the neural mechanism of tinnitus is a complex regulatory mechanism involving multiple networks. Future research is needed to study these neural networks more accurately to refine the tinnitus models.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.