ArticleFrontiers in neuroscience2021
Investigation of Risperidone Treatment Associated With Enhanced Brain Activity in Patients Who Stutter.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07734103 (A Single-Center, Double-Blind, Placebo-Controlled, Study to Evaluate Lumateperone, Flexible Doses of 21mg or 42mg in Patients With Moderate to Severe Childhood Onset Fluency Disorder, Stuttering.), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-Center, Double-Blind, Placebo-Controlled, Study to Evaluate Lumateperone, Flexible Doses of 21mg or 42mg in Patients With Moderate to Severe Childhood Onset Fluency Disorder, Stuttering.
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Evaluation of central auditory processing skills in children with stuttering.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- The synthetic self-hypothesis: dopaminergic redirection through self-face recognition in stuttering therapy.Frontiers in human neuroscience · 2026Article
- A stuttering-associatedbioRxiv : the preprint server for biology · 2025Article
- Iron dysregulation in mice engineered with a mutation associated with stuttering.bioRxiv : the preprint server for biology · 2025Article
- Stuttering: Our Current Knowledge, Research Opportunities, and Ways to Address Critical Gaps.Neurobiology of language (Cambridge, Mass.) · 2025Review
- Knowns and unknowns about the neurobiology of stuttering.PLoS biology · 2024Article
- Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective?Frontiers in human neuroscience · 2024Article
- Stuttering as a spectrum disorder: A hypothesis.Current research in neurobiology · 2023Review
- Epilepsy and Diagnostic Dilemmas: The Role of Language and Speech-Related Seizures.Journal of personalized medicine · 2022Review
- Morphometric analysis of astrocytes in vocal production circuits of common marmoset (Callithrix jacchus).The Journal of comparative neurology · 2022Article
- Phenome risk classification enables phenotypic imputation and gene discovery in developmental stuttering.American journal of human genetics · 2021Article
- Dopamine, vocalization, and astrocytes.Brain and language · 2021Article
- Stuttering: A Disorder of Energy Supply to Neurons?Frontiers in human neuroscience · 2021Article
- Speech Fluency Improvement in Developmental Stuttering Using Non-invasive Brain Stimulation: Insights From Available Evidence.Frontiers in human neuroscience · 2021Review
- Improvement of stuttering after administration of methylphenidate - a case report.Personalized medicine in psychiatryArticle
- Characterizing drug-induced stuttering in electronic health records.Journal of communication disordersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Stuttering is a childhood onset fluency disorder that leads to impairment in speech. A randomized, double-blinded placebo-controlled study was conducted with 10 adult subjects to observe the effects of risperidone (a dopamine receptor 2/serotonin receptor 2 antagonist) on brain metabolism, using [
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.