Evidence map›Paper›PMID 33642751›Full record

ArticleIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

Diagnostic Accuracy of Prebiopsy Ga-68 PSMA PET/CT in Detecting Primary Prostate Carcinomas with Prostate-Specific Antigen <50 ng/ml.

Piyush Chandra, Shanmugasundaram Rajaian, Karrthik Krishnamurthy, Lakshman Murugasen, Ganesan Chandran, John Santa Kumar, Satish Nath

Open access · greenAbstract read
In one paragraph

Article in Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Recurrent Prostate Cancer Diagnostics withDiagnostics (Basel, Switzerland) · 2022
    Review
  5. The Role of [Cancers · 2022
    Review
  6. Making the Case for Prostate-Specific Membrane Antigen-Targeted Positron Emission Tomography/Computed Tomography in Suspected Prostate Cancer.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Piyush ChandraDepartment of Nuclear Medicine, MIOT International Hospital, Chennai, Tamil Nadu, India.
Shanmugasundaram RajaianDepartment of Urology, MIOT International Hospital, Chennai, Tamil Nadu, India.
Karrthik KrishnamurthyDepartment of Urology, MIOT International Hospital, Chennai, Tamil Nadu, India.
Lakshman MurugasenDepartment of Urology, MIOT International Hospital, Chennai, Tamil Nadu, India.
Ganesan ChandranDepartment of Nuclear Medicine, MIOT International Hospital, Chennai, Tamil Nadu, India.
John Santa KumarDepartment of Nuclear Medicine, MIOT International Hospital, Chennai, Tamil Nadu, India.
Satish NathDepartment of Nuclear Medicine, MIOT International Hospital, Chennai, Tamil Nadu, India.
Madras Institute of Orthopaedics and Traumatology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimSerum prostate-specific-antigen (PSA) guided systematic transrectal ultrasound (TRUS)-guided biopsies are known to have a low predictive value in detection of primary prostate carcinomas (PCa). Our aim was to evaluate the accuracy of gallium-68 (Ga-68) prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) for the detection of PCa with serum PSA <50 ng/ml. PATIENTS AND

methodsWe retrospective analyzed prebiopsy Ga-68 PSMA PET/CT's of all patients with suspected PCa from October 2019 to March 2020. Several quantitative clinical and PET/CT variables were compared in benign and malignant groups and assessed for significance using an independent

resultsSixty-four patients were included with mean age 70 years (range 48-94 years); mean PSA 15.67 ng/ml (range 1.74-44), mean PSA density 0.32 ng/ml

conclusionGa-68 PSMA PET/CT can differentiate benign and malignant lesions of the prostate with very high accuracy and when used alongside with ERSPC3 calculator and magnetic resonance imaging, could potentially reduce painful and often unnecessary prostate biopsies.

Indexed as

BiopsycalculatorcancercarcinomaEuropean Randomized study for Screening of Prostate Cancergallium-68hyperplasiamagnetic resonance imagingpositron emission tomography/computed tomographyprostateprostate specific membrane antigenprostatitistransrectal ultrasound

Identifiers

PMID33642751
PMCPMC7905275
OpenAlexW3093974780

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.