ArticleHorticulture research2021
The Corylus mandshurica genome provides insights into the evolution of Betulaceae genomes and hazelnut breeding.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 28 citations in OpenAlex.
- Hazelnut allergome overview and Cor a gRNAs identification.BMC plant biology · 2025Article
- Genetic insights into developmental variations of spiny bracts among hazels through the pangenome construction.Plant biotechnology journal · 2025Article
- Genomic insights into ecological adaptation of oaks revealed by phylogenomic analysis of multiple species.Plant diversity · 2025Article
- A haplotype-resolved chromosome-level assembly and annotation of European hazelnut (C. avellana cv. Jefferson) provides insight into mechanisms of eastern filbert blight resistance.G3 (Bethesda, Md.) · 2024Article
- The first two chromosome-scale genome assemblies of American hazelnut enable comparative genomic analysis of the genus Corylus.Plant biotechnology journal · 2024Article
- SiMul-db: a database of single and multi-target Cas9 guides for hazelnut editing.Frontiers in genetics · 2024Article
- Population genomics reveals demographic history and selection signatures of hazelnut (Horticulture research · 2023Article
- From comparative gene content and gene order to ancestral contigs, chromosomes and karyotypes.Scientific reports · 2023Article
- GRAS-Di SNP-based molecular characterization and fingerprinting of a Turkish Corylus avellana core set provide insights into the cultivation and breeding of hazelnut in Turkey.Molecular genetics and genomics : MGG · 2023Article
- The Current Developments in Medicinal Plant Genomics Enabled the Diversification of Secondary Metabolites' Biosynthesis.International journal of molecular sciences · 2022Review
- First rhyncaphytoptine mite (Eriophyoidea, Diptilomiopidae) parasitizing American hazelnut (Corylus americana): molecular identification, confocal microscopy, and phylogenetic position.Experimental & applied acarology · 2022Article
- Celebrating Mendel, McClintock, and Darlington: On end-to-end chromosome fusions and nested chromosome fusions.The Plant cell · 2022Review
- Molecular signatures of parallel adaptive divergence causing reproductive isolation and speciation across two genera.Innovation (Cambridge (Mass.)) · 2022Article
- Genomic evidence for homoploid hybrid speciation between ancestors of two different genera.Nature communications · 2022Article
- Chromosome-level genome assembly provides new insights into Japanese chestnut (Frontiers in plant science · 2022Article
- Chromosome-Level Genome Assembly and HazelOmics Database Construction Provides Insights Into Unsaturated Fatty Acid Synthesis and Cold Resistance in Hazelnut (Frontiers in plant science · 2021Article
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hazelnut is popular for its flavor, and it has also been suggested that hazelnut is beneficial to cardiovascular health because it is rich in oleic acid. Here, we report the first high-quality chromosome-scale genome for the hazelnut species Corylus mandshurica (2n = 22), which has a high concentration of oleic acid in its nuts. The assembled genome is 367.67 Mb in length, and the contig N50 is 14.85 Mb. All contigs were assembled into 11 chromosomes, and 28,409 protein-coding genes were annotated. We reconstructed the evolutionary trajectories of the genomes of Betulaceae species and revealed that the 11 chromosomes of the hazelnut genus were derived from the most ancestral karyotype in Betula pendula, which has 14 protochromosomes, by inferring homology among five Betulaceae genomes. We identified 96 candidate genes involved in oleic acid biosynthesis, and 10 showed rapid evolution or positive selection. These findings will help us to understand the mechanisms of lipid synthesis and storage in hazelnuts. Several gene families related to salicylic acid metabolism and stress responses experienced rapid expansion in this hazelnut species, which may have increased its stress tolerance. The reference genome presented here constitutes a valuable resource for molecular breeding and genetic improvement of the important agronomic properties of hazelnut.
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