Evidence map›Paper›PMID 33642484›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Marked Respiratory Failure in an Ambulant Patient with Immune-mediated Necrotizing Myopathy and Anti-Kv1.4 and Anti-titin Antibodies.

Atsuhiko Sugiyama, Yosuke Onishi, Kimiko Ito, Kazumoto Shibuya, Keigo Nakamura, Fumiko Oda, Ichizo Nishino, Shigeaki Suzuki, Satoshi Kuwabara

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Atsuhiko SugiyamaDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Yosuke OnishiDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Kimiko ItoDepartment of Neurology, National Hospital Organization Chibahigashi National Hospital, Japan.
Kazumoto ShibuyaDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Keigo NakamuraDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Fumiko OdaDepartment of Neurology, National Hospital Organization, Chiba Medical Center, Japan.
Ichizo NishinoNeurological Research Institute, National Center of Neurology and Psychiatry, Japan.
Shigeaki SuzukiDepartment of Neurology Keio University School of Medicine, Japan.
Satoshi KuwabaraDepartment of Neurology, Graduate School of Medicine, Chiba University, Japan.
Chiba University · JPNational Hospital Organization · JPKeio University · JPNational Center of Neurology and Psychiatry · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of seronegative immune-mediated necrotizing myopathy (IMNM) concurrent with anti-Kv1.4 and anti-titin antibodies. A 72-year-old Japanese woman presented with a 29-year history of fluctuating high serum creatine kinase (CK) levels followed by intermittent ptosis and respiratory muscle weakness. This case highlights the fact that marked respiratory muscle weakness requiring intubation can be seen in an ambulant patient with IMNM. Marked respiratory muscle weakness, rhabdomyolysis-like acute elevation of CK levels, and anti-striational muscle antibodies may be a characteristic constellation of findings in a distinct subgroup of patients with inflammatory myopathy with myasthenia gravis or similar symptoms.

Indexed as

Muscular DiseasesMyasthenia GravisMyositisRespiratory InsufficiencyAgedAutoantibodiesFemaleHumansMuscle WeaknessAutoantibodiesblepharoptosiscreatine kinasemuscular diseasesrespiratory paralysis

Identifiers

PMID33642484
PMCPMC8429292
OpenAlexW3133565927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.