Evidence map›Paper›PMID 33641621›Full record

Trial reportSAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance2021

Maternal and infant antiretroviral therapy adherence among women living with HIV in rural South Africa: a cluster randomised trial of the role of male partner participation on adherence and PMTCT uptake.

Deborah L Jones, Violeta J Rodriguez, Manasi Soni Parrish, Tae Kyoung Lee, Stephen M Weiss, Shandir Ramlagan, Karl Peltzer

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Deborah L JonesDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-4106-8891
Violeta J RodriguezDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0001-8543-2061
Manasi Soni ParrishDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-6077-8768
Tae Kyoung LeeDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Stephen M WeissDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0001-6266-6148
Shandir RamlaganHIV/AIDS/STIs and TB (HAST) Research Programme, Human Sciences Research Council, Pretoria, South Africa.ORCID 0000-0001-9906-4474
Karl PeltzerDepartment for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City, Vietnam.ORCID 0000-0002-5980-0876
University of Miami · USHuman Sciences Research Council · ZATon Duc Thang University · VN

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GWENDOLYN Barbara SCOTT · 2007 to 2026
$33.8M
Implementing Comprehensive PMTCT and HIV Prevention for South African CouplesR01HD078187 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JONES, DEBORAH LYNNE, PELTZER, KARL F · 2013 to 2017
$2.8M
NIAID NIH HHS P30 AI073961NICHD NIH HHS R01 HD078187
6 · The paper itself

Abstract

'Mother-to-child transmission of HIV' can occur during the period of pregnancy, childbirth, or breastfeeding. 'Prevention of mother-to-child transmission of HIV' (PMTCT) in Mpumalanga Province, South Africa, is especially vital as the prevalence of HIV is 28.2% in women aged 15-49. PMTCT interventions resulted in a drop of MTCT rates in Mpumalanga from ∼2% in 2015 to 1.3% in 2016. This randomised controlled trial in Mpumalanga examined the potential impact of a lay healthcare worker administered intervention, 'Protect Your Family', on maternal and infant adherence, and to assess the relative influence of male partner involvement on infant and maternal adherence. This cluster randomised controlled trial used a two-phase and two-condition (experimental or control) study design where participants (

Indexed as

Anti-HIV AgentsHIV InfectionsPregnancy Complications, InfectiousAnti-Retroviral AgentsFemaleHumansInfantInfectious Disease Transmission, VerticalMalePregnancySouth AfricaAnti-HIV AgentsAnti-Retroviral AgentsadherenceHIVmale involvementSouth Africawomen

Identifiers

PMID33641621
PMCPMC7919911
OpenAlexW3134726846

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.