Evidence map›Paper›PMID 33641517›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Change and predictive ability of circulating immunoregulatory lymphocytes in long-term outcomes of acute ischemic stroke.

Sicheng Li, Yichen Huang, Yang Liu, Marcelo Rocha, Xiaofan Li, Pengju Wei, Dilidaer Misilimu, Yunhe Luo, Jing Zhao, Yanqin Gao

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Isolation and identification of leukocyte populations in intracranial blood collected during mechanical thrombectomy.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Trial
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Salvianolic acid A enhances TArchives of pharmacal research · 2025
    Article
  11. Review
  12. Treg Upregulation by Treadmill Training Accelerates Myelin Repair Post-Ischemia.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  13. CD4Frontiers in immunology · 2025
    Review
  14. The influence of gender on CD4Frontiers in neurology · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sicheng LiState Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, China.
Yichen HuangState Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, China.
Yang LiuDepartment of Neurology, Minhang Hospital Affiliated to Fudan University, Shanghai, China.
Marcelo RochaDepartment of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-4503-5827
Xiaofan LiDepartment of Neurology, Minhang Hospital Affiliated to Fudan University, Shanghai, China.
Pengju WeiState Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, China.
Dilidaer MisilimuState Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, China.
Yunhe LuoDepartment of Neurology, Minhang Hospital Affiliated to Fudan University, Shanghai, China.
Jing ZhaoDepartment of Neurology, Minhang Hospital Affiliated to Fudan University, Shanghai, China.
Yanqin GaoState Key Laboratory of Medical Neurobiology, MOE Frontier Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, China.ORCID 0000-0002-4915-9819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphocytes play an important role in the immune response after stroke. However, our knowledge of the circulating lymphocytes in ischemic stroke is limited. Herein, we collected the blood samples of clinical ischemic stroke patients to detect the change of lymphocytes from admission to 3 months after ischemic stroke by flow cytometry. A total of 87 healthy controls and 210 patients were enrolled, and the percentages of circulating T cells, CD4

Indexed as

Acute DiseaseFlow CytometryHumansImmunityIschemic StrokeLymphocytesCirculating lymphocytesflow cytometryischemic strokeregulatory B cellsregulatory T cells

Identifiers

PMID33641517
PMCPMC8393304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.