Observational studyThe Journal of international medical research2021
Pediatric characteristics and the dose of propofol for sedation during radiological examinations: a retrospective analysis.
Observational study in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Associations between protocol-related operational factors, MRI duration, and propofol exposure in pediatric MRI.Pediatric radiology · 2026Article
- A Single-Center Retrospective Analysis of a Standardized Sedation Protocol for MRI in Children with Achondroplasia: Minimal Complications and Excellent Imaging Quality.Children (Basel, Switzerland) · 2025Article
- A Novel Propofol Dosing Regimen for Pediatric Sedation during Radiologic Tests.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe present study aimed to investigate patients' characteristics that can affect the dose of propofol required to sedate children undergoing imaging.
methodsIn this retrospective, observational study, we reviewed medical records of children aged 0 to 18 years who were classified as having American Society of Anesthesiologists status 1 or 2 and they underwent imaging under propofol sedation between January 2011 and August 2016. Collected data included patients' demographics, propofol doses, duration of sedation, and complications. Regression analysis was performed to determine patients' characteristics that may affect the dose of propofol required to induce sedation.
resultsA total of 925 patients were included. Simple linear regression showed that the dose of propofol was correlated with age, height, weight, and body surface area. Using the results of multiple linear regression, the following formula was used to estimate the dose of propofol (mg) for sedation: 0.75 + 0.14 × age (months) + 45.82 × body surface area (m
conclusionA child's age, height, and body surface area should be considered when deciding the induction dose of propofol. Additionally, the formula that we have proposed can be used to estimate the dose of propofol required to induce sedation in children undergoing imaging.
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