Evidence map›Paper›PMID 33641357›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

TRPV1 (Transient Receptor Potential Vanilloid 1) Sensitization of Skeletal Muscle Afferents in Type 2 Diabetic Rats With Hyperglycemia.

Rie Ishizawa, Han-Kyul Kim, Norio Hotta, Gary A Iwamoto, Jere H Mitchell, Scott A Smith, Wanpen Vongpatanasin, Masaki Mizuno

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Epidemiological and mechanistic links between PMFrontiers in endocrinology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Sex-dependent attenuating effects of capsaicin administration on the mechanoreflex in healthy rats.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  15. The exercise pressor reflex: An update.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rie IshizawaFrom the Departments of Applied Clinical Research (R.I., S.A.S., M.M.), University of Texas Southwestern Medical Center, Dallas.
Han-Kyul KimInternal Medicine (H.-K.K., J.H.M., S.A.S., W.V., M.M.), University of Texas Southwestern Medical Center, Dallas.
Norio HottaCollege of Life and Health Sciences, Chubu University, Kasugai, Japan (N.H.).
Gary A IwamotoCell Biology (G.A.I.), University of Texas Southwestern Medical Center, Dallas.
Jere H MitchellInternal Medicine (H.-K.K., J.H.M., S.A.S., W.V., M.M.), University of Texas Southwestern Medical Center, Dallas.
Scott A SmithFrom the Departments of Applied Clinical Research (R.I., S.A.S., M.M.), University of Texas Southwestern Medical Center, Dallas.
Wanpen VongpatanasinInternal Medicine (H.-K.K., J.H.M., S.A.S., W.V., M.M.), University of Texas Southwestern Medical Center, Dallas.
Masaki MizunoFrom the Departments of Applied Clinical Research (R.I., S.A.S., M.M.), University of Texas Southwestern Medical Center, Dallas.
The University of Texas Southwestern Medical Center · USChubu University · JP

Funding

UT Southwestern O'Brien Kidney Research Core CenterP30DK079328 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MOE, ORSON W · 2007 to 2021
$16.9M
Preventing Hypertension and Sympathetic Overactivation by Targeting PhosphateR01HL133179 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI SMITH, SCOTT A, VONGPATANASIN, WANPEN · 2017 to 2020
$3.2M
TARGETING INSULIN RESISTANCE TO IMPROVE ABNORMAL CARDIOVASCULAR CONTROL IN DIABETESR01HL151632 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MIZUNO, MASAKI · 2020 to 2023
$1.8M
NHLBI NIH HHS R01 HL133179NHLBI NIH HHS R01 HL151632NIDDK NIH HHS P30 DK079328
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Diabetes Mellitus, Type 2Ganglia, SpinalHyperglycemiaMuscle, SkeletalAnimalsBlood PressureCapsaicinEvoked PotentialsNeurons, AfferentPhysical Conditioning, AnimalProtein Kinase CRatsRats, Sprague-DawleyTRPV Cation ChannelsCapsaicinProtein Kinase CTrpv1 protein, ratTRPV Cation Channelsblood pressureexerciseglucosemusclesneurons

Identifiers

PMID33641357
PMCPMC8109832
OpenAlexW3135150292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.