Evidence map›Paper›PMID 33641039›Full record

ReviewArchives of microbiology2021

Modulation of quorum sensing-associated virulence in bacteria: carbohydrate as a key factor.

Sarika Suresh, Prathiksha Prabhakara Alva, Ramya Premanath

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarika SureshNitte (Deemed To Be University), Nitte University Centre for Science Education and Research, Paneer Campus, Deralakatte, Mangalore, Karnataka, 575018, India.
Prathiksha Prabhakara AlvaNitte (Deemed To Be University), Nitte University Centre for Science Education and Research, Paneer Campus, Deralakatte, Mangalore, Karnataka, 575018, India.
Ramya PremanathNitte (Deemed To Be University), Nitte University Centre for Science Education and Research, Paneer Campus, Deralakatte, Mangalore, Karnataka, 575018, India. ramya@nitte.edu.in.ORCID http://orcid.org/0000-0001-5144-8241
Nitte University · IN

Funding

Nitte NUFR2/2018/10/27
6 · The paper itself

Abstract

Quorum sensing (QS) is a method of inter-cellular communication that permits bacteria to dispense information about cell density and to synchronize the gene expression accordingly. Gram-positive and Gram-negative bacteria utilize distinct quorum sensing mechanisms for effective pathogenesis. Virulence factor production by pathogenic bacteria is one of the important traits that is under the control of QS. A growing body of evidence has indicated the role of the nutritional environment notably by carbohydrates in dictating the QS-associated virulence gene regulation. The modulation of QS by carbohydrates mitigates the survival and establishment of the pathogen within its host which in turn leads to an increase in morbidity and mortality. This mini-review throws light on the predilection of pathogenic bacteria to rapidly regulate its QS-linked virulence gene expression based on the changing nutrient levels that assist them in prospering within diverse niches.

Indexed as

BacteriaCarbohydratesGene Expression Regulation, BacterialGram-Negative BacteriaGram-Positive BacteriaMicrobial ViabilityQuorum SensingVirulenceVirulence FactorsCarbohydratesVirulence FactorsCarbohydratesGram-negative bacteriaGram-positive bacteriaQuorum sensingVirulence

Identifiers

PMID33641039
OpenAlexW3134520388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.