Evidence map›Paper›PMID 33640879›Full record

ArticleAging2021

Neuroprotective effect of hydrogen sulfide against glutamate-induced oxidative stress is mediated via the p53/glutaminase 2 pathway after traumatic brain injury.

Jianping Sun, Xiaoyu Li, Xiaoyu Gu, Hailong Du, Gengshen Zhang, Jianliang Wu, Feng Wang

Abstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. The role of hydrogen sulfide regulation of ferroptosis in different diseases.Apoptosis : an international journal on programmed cell death · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianping SunDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Xiaoyu LiDepartment of Thyroid and Breast Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Xiaoyu GuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Hailong DuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Gengshen ZhangDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Jianliang WuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.
Feng WangDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several reports suggest that hydrogen sulfide (H

Indexed as

AnimalsApoptosisBrain EdemaBrain Injuries, TraumaticDisease Models, AnimalGlutamic AcidHydrogen SulfideMorris Water Maze TestNeuroprotective AgentsOxidative StressRatsRats, Sprague-DawleySignal TransductionSpatial MemoryTransaminasesTumor Suppressor Protein p53Glutamic Acidglutamine-pyruvate aminotransferaseHydrogen SulfideNeuroprotective AgentsTransaminasesTumor Suppressor Protein p53glutamatehydrogen sulfideoxidative stressp53traumatic brain injury

Identifiers

PMID33640879
PMCPMC7993660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.