Evidence map›Paper›PMID 33640717›Full record

ReviewJournal of neuroimmunology2021

Acute transverse myelitis with Dysautonomia following SARS-CoV-2 infection: A case report and review of literature.

Maria Camila Moreno-Escobar, Saurabh Kataria, Erum Khan, Roshan Subedi, Medha Tandon, Krithika Peshwe, Joshua Kramer, Faraze Niaze, Shitiz Sriwastava

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Journal of neuroimmunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  10. Autonomic dysfunction in non-critically ill COVID-19 patients during the acute phase of disease: an observational, cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Observational
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  18. Neurological update: COVID-19.Journal of neurology · 2021
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Maria Camila Moreno-EscobarDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.
Saurabh KatariaDepartment of Neurology, University of Missouri Healthcare, Columbia, MO, USA.
Erum KhanB.J. Medical College and Civil hospital, Ahmedabad, India.
Roshan SubediInstitute of Medicine, Kathmandu, Nepal.
Medha TandonSafdarjung Hospital, India.
Krithika PeshweDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.
Joshua KramerDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.
Faraze NiazeDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.
Shitiz SriwastavaDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA; West Virginia Clinical Transitional Science, Morgantown, WV, USA. Electronic address: shitiz.sriwastava@hsc.wvu.edu.
West Virginia University · USB.J. Medical College · INSafdarjang Hospital · INUniversity of Missouri Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report a unique case and literature review of post COVID-19 associated transverse myelitis and dysautonomia with abnormal MRI and CSF findings.

backgroundCoronavirus disease have been reported to be associated with several neurological manifestations such as stroke, Guillain-Barré syndrome, meningoencephalitis amongst others. There are only few reported cases of transverse myelitis with the novel coronavirus (n-CoV-2) and only one reported case identifying dysautonomia in COVID-19 patient. Here, we identify a COVID-19 patient diagnosed with acute transverse myelitis in addition to dysautonomia following with complete resolution of symptoms.

methodA retrospective chart review of a patient diagnosed with post SARS-CoV-2 infection acute transverse myelitis and dysautonomia, and a review of literature of all the reported cases of transverse myelitis and COVID-19, from December 1st, 2019 till December 25th, 2020, was performed.

conclusionTo our knowledge, this is the first reported case of transverse myelitis and dysautonomia in a patient with SARS-CoV-2 infection, who responded to intravenous methyl prednisone and bromocriptine. Follow-up imaging of the spine showed complete resolution of the lesion. Further studies would be recommended to identify the underlying correlation between COVID-19 and transverse myelitis.

Indexed as

AdultAnti-Inflammatory AgentsBromocriptineCOVID-19Dopamine AgonistsHumansMaleMethylprednisoloneMyelitis, TransversePrimary DysautonomiasSARS-CoV-2Spinal CordAnti-Inflammatory AgentsBromocriptineDopamine AgonistsMethylprednisoloneAutoimmune disorderCoronavirus disease 2019COVID-19DysautonomiaMRI spineSARS-CoV-2Transverse myelitis

Identifiers

PMID33640717
PMCPMC7895682
OpenAlexW3131806568

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.