Evidence map›Paper›PMID 33640399›Full record

ArticlePreventive medicine2021

Temporal changes in allostatic load patterns by age, race/ethnicity, and gender among the US adult population; 1988-2018.

Justin Xavier Moore, Malcolm S Bevel, Stella Aslibekyan, Tomi Akinyemiju

Abstract read
In one paragraph

Article in Preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Examining the Role of the Social Vulnerability Index in the Association between Race/Ethnicity and Breast Cancer Outcomes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Allostatic Load, Multimorbidity, and Overall and Cancer-Specific Survival among Older Adults in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Big-5 personality traits as predictors of allostatic load in Latino Americans: a longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Allostatic load and cognitive recall among young adults: Racial, ethnic, and sex-specific variations.Journal of the International Neuropsychological Society : JINS · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Justin Xavier MooreDivision of Epidemiology, Department of Population Health Sciences, Augusta University, Augusta, GA, USA; Institute of Preventive and Public Health, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Malcolm S BevelDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
Stella AslibekyanDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Tomi AkinyemijuDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA. Electronic address: tomi.akinyemiju@duke.edu.

Funding

Metabolic Syndrome and Epigenetic Markers of Breast Cancer in Nigerian WomenK01TW010271 · FIC · UNIVERSITY OF KENTUCKY · PI AKINYEMIJU, TOMI F · 2016 to 2020
$676k
Geographic and Racial Disparities in Mammography Screening and Barriers to Receiving CareK01MD015304 · NIMHD · UNIVERSITY OF KENTUCKY · PI MOORE, JUSTIN XAVIER · 2020 to 2024
$646k
FIC NIH HHS K01 TW010271NIMHD NIH HHS K01 MD015304
6 · The paper itself

Abstract

The objective of this study is to provide an assessment of allostatic load (AL) burden among US adults across race/ethnicity, gender, and age groups over a 30-year time period. We analyzed data from 50,671 participants of the National Health and Nutrition Examination Survey (NHANES) years 1988 through 2018. AL score was defined as the sum total for abnormal measures of the following components: serum albumin, body mass index, serum C - reactive protein, serum creatinine, diastolic blood pressure, glycated hemoglobin, systolic blood pressure, total cholesterol, and serum triglycerides. We performed modified Poisson regression to estimate the adjusted Relative Risks (aRRs) of allostatic load, and generalized linear models to determine adjusted mean differences accounting for NHANES sampling weights. Among US adults aged 18 or older, the prevalence of high AL increased by more than 45% from 1988 to 1991 to 2015-2018, from 33.5% to 48.6%. By the latest period, 2015-2018, Non-Hispanic Black women (aRR: 1.292; 95% CI: 1.290-1.293) and Latina women (aRR: 1.266; 95% CI: 1.265-1.267) had higher risks of AL than non-Hispanic White women. Similar trends were observed among men. Age-adjusted mean AL score among NH-Black and Latinx adults was higher than for NH-Whites of up to a decade older regardless of gender. From 1988 through 2018, Adults aged 40 years old and older had over 2-fold increased risks of high AL when compared to adults 18-29 years old. After 30-years of collective data, racial disparities in allostatic load persist for NH-Black and Latinx adults.

Indexed as

AllostasisAdolescentAdultBlack or African AmericanEthnicityFemaleHispanic or LatinoHumansMaleNutrition SurveysUnited StatesYoung AdultCumulative stressDisparitiesLife-coursePsychosocial stressRace

Identifiers

PMID33640399
PMCPMC8826516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.