Evidence map›Paper›PMID 33640031›Full record

ArticleAntimicrobial resistance and infection control2021

Systematic screening on admission for SARS-CoV-2 to detect asymptomatic infections.

Rahel N Stadler, Laura Maurer, Lisandra Aguilar-Bultet, Fabian Franzeck, Chantal Ruchti, Richard Kühl, Andreas F Widmer, Ruth Schindler, Roland Bingisser, Katharina M Rentsch and 10 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Pooled it
  2. Article
  3. Observational
  4. Article
  5. ESCMID guidelines on testing for SARS-CoV-2 in asymptomatic individuals to prevent transmission in the health care setting.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Epidemiology of COVID-19: What changed in one year?Turkish journal of medical sciences · 2021
    Review
  10. Article
  11. Sort and Sieve: Pre-Triage Screening of Patients with Suspected COVID-19 in the Emergency Department.International journal of environmental research and public health · 2021
    Observational
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 2 countries.

Rahel N StadlerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Laura MaurerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Lisandra Aguilar-BultetDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Fabian FranzeckDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Chantal RuchtiDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Richard KühlDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Andreas F WidmerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Ruth SchindlerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Roland BingisserEmergency Department, University Hospital Basel, University of Basel, Basel, Switzerland.
Katharina M RentschLaboratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Hans ParggerIntensive Care Unit, University Hospital Basel, University of Basel, Basel, Switzerland.
Raoul SutterIntensive Care Unit, University Hospital Basel, University of Basel, Basel, Switzerland.
Luzius SteinerAnesthesiology, University Hospital Basel, University of Basel, Basel, Switzerland.
Christoph MeierUniversity Hospital Basel, University of Basel, Basel, Switzerland.
Werner KüblerUniversity Hospital Basel, University of Basel, Basel, Switzerland.
Hans H HirschDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Adrian EgliClinical Microbiology, University Hospital Basel, University of Basel, Basel, Switzerland.
Manuel BattegayDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Stefano BassettiInternal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Sarah Tschudin-SutterDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Petersgraben 4, 4031, Basel, Switzerland. sarah.tschudin@usb.ch.ORCID 0000-0003-4875-5368
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proportion of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains elusive and the potential benefit of systematic screening during the SARS-CoV-2-pandemic is controversial. We investigated the proportion of asymptomatic inpatients who were identified by systematic screening for SARS-CoV-2 upon hospital admission. Our analysis revealed that systematic screening of asymptomatic inpatients detects a low total number of SARS-CoV-2 infections (0.1%), questioning the cost-benefit ratio of this intervention. Even when the population-wide prevalence was low, the proportion of asymptomatic carriers remained stable, supporting the need for universal infection prevention and control strategies to avoid onward transmission by undetected SARS-CoV-2-carriers during the pandemic.

Indexed as

AgedAsymptomatic InfectionsCost-Benefit AnalysisCOVID-19COVID-19 TestingFemaleHumansMaleMass ScreeningMiddle AgedSARS-CoV-2SwitzerlandAsymptomatic carriersCOVID-19SARS-CoV-2Screening

Identifiers

PMID33640031
PMCPMC7912536
OpenAlexW3134087986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.