SynthesisCritical care (London, England)2021
Energy delivery guided by indirect calorimetry in critically ill patients: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of early enteral nutrition in patients with traumatic brain injury: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Energy and protein nutrition adequacy in general wards among intensive care unit survivors: A systematic review and meta-analysis.JPEN. Journal of parenteral and enteral nutrition · 2025Pooled it
- Effects of Energy Delivery Guided by Indirect Calorimetry in Critically Ill Patients: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Pooled it
- Indirect calorimetry-guided nutrition during weaning from prolonged mechanical ventilation: a double-blind randomized controlled trial.Critical care (London, England) · 2026Trial
- Indirect calorimetry and nitrogen balance guided nutrition therapy in ICU patients with acute kidney injury.Scientific reports · 2025Trial
- Personalised energy targeting during venovenous ECMO: serial assessment of resting energy expenditure reveals phase-dependent metabolic demand and systematic discordance with predictive equations.Critical care (London, England) · 2026Article
- Measured resting energy expenditure via indirect calorimetry of critically ill patients: A comparison with predictive equations.Asia Pacific journal of clinical nutrition · 2026Article
- Article
- Precision nutrition in critical illness: a phase-specific framework from acute feeding to post-ICU recovery.Frontiers in nutrition · 2026Review
- Phase-Related Resting Energy Expenditure in Critically Ill Adults: Metabolic Phenotypes and Determinants of Weight-Normalized Indices-A Retrospective Study.Journal of clinical medicine · 2025Article
- Towards optimised nutrition therapy after critical illness: a position statement and research framework by the global research initiative on post-intensive care nutrition (GRIP) consortium.Critical care (London, England) · 2025Review
- Nutritional Adequacy and Day-to-Day Energy Variability: Impacts on Outcomes in Severe Trauma Patients.Nutrients · 2025Observational
- Novel Strategies to Promote Intensive Care Unit Recovery via Personalized Exercise, Nutrition, and Anabolic Interventions.Critical care clinics · 2025Review
- The Japanese Critical Care Nutrition Guideline 2024.Journal of intensive care · 2025Review
- Accuracy of bedside ultrasound for predicting resting energy expenditure in critically ill patients: A feasibility study.PloS one · 2025Article
- Nutritional Optimization of the Surgical Patient: A Narrative Review.Advances in nutrition (Bethesda, Md.) · 2025Review
- Beyond Calories: Individual Metabolic and Hormonal Adaptations Driving Variability in Weight Management-A State-of-the-Art Narrative Review.International journal of molecular sciences · 2024Review
- Personalized Nutrition in the Pediatric ICU: Steering the Shift from Acute Stress to Metabolic Recovery and Rehabilitation.Nutrients · 2024Review
- Observational
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of indirect calorimetry (IC) is increasing due to its precision in resting energy expenditure (REE) measurement in critically ill patients. Thus, we aimed to evaluate the clinical outcomes of an IC-guided nutrition therapy compared to predictive equations strategy in such a patient population.
methodsWe searched PubMed, EMBASE, and Cochrane library databases up to October 25, 2020. Randomized controlled trials (RCTs) were included if they focused on energy delivery guided by either IC or predictive equations in critically ill adults. We used the Cochrane risk-of-bias tool to assess the quality of the included studies. Short-term mortality was the primary outcome. The meta-analysis was performed with the fixed-effect model or random-effect model according to the heterogeneity.
resultsEight RCTs with 991 adults met the inclusion criteria. The overall quality of the included studies was moderate. Significantly higher mean energy delivered per day was observed in the IC group, as well as percent delivered energy over REE targets, than the control group. IC-guided energy delivery significantly reduced short-term mortality compared with the control group (risk ratio = 0.77; 95% CI 0.60 to 0.98; I
conclusionsThis meta-analysis indicates that IC-guided energy delivery significantly reduces short-term mortality in critically ill patients. This finding encourages the use of IC-guided energy delivery during critical nutrition support. But more high-quality studies are still needed to confirm these findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.