Evidence map›Paper›PMID 33639980›Full record

ArticleHealth and quality of life outcomes2021

Assessment of the health utility of patients with leukemia in China.

Xueyun Zeng, Mingjie Sui, Rui Liu, Xinyu Qian, Wenfeng Li, Erwei Zheng, Jinjin Yang, Jinmei Li, Weidong Huang, Hongbin Yang and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Health and quality of life outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Agreement between the EQ-5D-5L anxiety/depression dimension and GAD-7/PHQ-9 for psychological distress assessment in patients with hematologic malignancies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Quality of life of patients with hematological malignancies and factors affecting health state utility values.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xueyun Zeng *School of Health Management, Harbin Medical University, Harbin, 150086, China.
Mingjie Sui *School of Health Management, Harbin Medical University, Harbin, 150086, China.
Rui Liu *School of Health Management, Harbin Medical University, Harbin, 150086, China.
Xinyu QianNational University Singapore Saw Swee Hock School of Public Health, Singapore, 117549, Singapore.
Wenfeng LiDepartment of Hematology, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Erwei ZhengFirst Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Jinjin YangSchool of Health Management, Harbin Medical University, Harbin, 150086, China.
Jinmei LiPublic Health Education and Information Center of Heilongjiang Province, Harbin, 150063, China.
Weidong HuangSchool of Health Management, Harbin Medical University, Harbin, 150086, China. weidong218@126.com.ORCID http://orcid.org/0000-0003-2798-4735
Hongbin YangDepartment of Medical Oncology, Third Affiliated Hospital of Harbin Medical University, Harbin, 150081, China. Yang21hongbin@163.com.
Hongjuan YuDepartment of Hematology, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. yuhongjuan2008@163.com.
Nan LuoNational University Singapore Saw Swee Hock School of Public Health, Singapore, 117549, Singapore.

Funding

the China Medical Board CMB-19-308the National Social Science Foundation of China 71503062the National Social Science Foundation of China 71974048
6 · The paper itself

Abstract

objectivesThis study aimed to assess the health utility of leukemia patients in China using the EQ-5D-5L, compare it with the population norms, and identify the potential factors associated with health utility.

methodsA hospital based cross-sectional survey was conducted in three tertiary hospitals from July 2015 to February 2016. A total of 186 patients with leukemia completed the EQ-5D-5L and their health utility scores were calculated using the Chinese value set. EQ-5D-5L utility and dimensions scores of leukemia patients were compared with China's population norms using Kruskal-Wallis test and chi square test. Potential factors associated with health utility were identified using Tobit regression.

resultsThe mean EQ-5D-5L utility scores of patients with leukemia, grouped by either gender or age, were significantly lower than those of the general population (p < 0.001). The same results were found for individual dimensions of EQ-5D-5L, where leukemia patients reported more health problems than the general population (p < 0.001). The utility score of leukemia patients was found to be significantly related to medical insurance, religious belief, comorbidities, social support and ECOG performance status.

conclusionThis study indicated that leukemia patients have worse health status compared to the general population of China and that multiple factors affect the health utility of the patients. The utility scores reported in this study could be useful in future cost-utility analysis.

Indexed as

Health StatusQuality of LifeAdultChinaCross-Sectional StudiesFemaleHumansLeukemiaMaleMiddle AgedSocial SupportSurveys and QuestionnairesCancerEQ-5D-5LHealth utilityLeukemia

Identifiers

PMID33639980
PMCPMC7913428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.