ArticleSubstance abuse treatment, prevention, and policy2021
Substance use and symptoms of mental health disorders: a prospective cohort of patients with severe substance use disorders in Norway.
Article in Substance abuse treatment, prevention, and policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Risk and protective factors for relapse after residential substance use treatment: a systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- Trial
- Effect of integrated hepatitis C virus treatment on psychological distress in people with substance use disorders.Scientific reports · 2024Trial
- Association between venlafaxine use and the risk of withdrawal from nonopioid substances: a nationwide, population-based study.Harm reduction journal · 2026Article
- Article
- Low Testosterone Among Males in Opioid Agonist Therapy and Its Association With Fatigue and Psychological Distress.Journal of the Endocrine Society · 2025Article
- Mental health nurses' experiences of caring for inpatients with severe mental disorders: a qualitative study.BMC psychiatry · 2025Article
- Experiences with healthy eating among individuals with opioid dependence: insights from a dietary assessment.BMC nutrition · 2025Article
- Associations between happiness with social factors and opioid agonist therapy among people who inject drugs.Scientific reports · 2025Article
- Examining the Role of Posttraumatic Stress and Depressive Symptoms in HIV Pre-exposure Prophylaxis (PrEP) Motivation Among Women Survivors of Intimate Partner Violence.AIDS and behavior · 2025Article
- Collaborative work processes in establishing a MiniMaria treatment center for youth substance addiction: a qualitative inquiry of county council healthcare and municipal efforts.BMC health services research · 2024Article
- Change in substance use among patients in opioid maintenance treatment: baseline to 1-year follow-up.Harm reduction journal · 2024Article
- Exploring dual diagnosis in opioid agonist treatment patients: a registry-linkage study in Czechia and Norway.Addiction science & clinical practice · 2024Article
- Liver stiffness and associated risk factors among people with a history of injecting drugs: a prospective cohort study.Substance abuse treatment, prevention, and policy · 2024Article
- Article
- Validation of the UPPS-P Impulsive Behavior Scale and Clinical Correlates of its Scores in French-Speaking Patients Starting a Residential Detoxification Program.Indian journal of psychological medicine · 2023Article
- Climate Change and Substance-Use Behaviors: A Risk-Pathways Framework.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- A qualitative study on people with opioid use disorders' perspectives on smoking and smoking cessation interventions.Frontiers in psychiatry · 2023Article
- Diagnostic capabilities of self-reported psychoactive substance use among patients admitted to psychiatric consultations in Benin, West Africa.BMC psychiatry · 2022Article
- Experiences of Hope after Treatment of Hepatitis C Infection-A Qualitative Study.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThere is high co-occurrence of substance use disorders (SUD) and mental health disorders. We aimed to assess impact of substance use patterns and sociodemographic factors on mental health distress using the ten-item Hopkins Symptom Checklist (SCL-10) over time.
methodsNested prospective cohort study of 707 participants with severe SUD across nine opioid-agonist-therapy outpatient clinics and low-threshold municipality clinics in Norway, during 2017-2020. Descriptive statistics were derived at baseline and reported by means and standard deviation (SD). A linear mixed model analysis was used to assess the impact of substance use patterns and sociodemographic factors on SCL-10 sum score with beta coefficients with 95% confidence intervals (CI).
resultsMean (SD) SCL-10 score was 2.2 (0.8) at baseline with large variations across patients. We observed more symptoms of mental health disorders among people with frequent use of benzodiazepines (beta 3.6, CI:2.4;4.8), cannabis (1.3, CI:0.2;2.5), opioids (2.7, CI:1.1;4.2), and less symptoms among people using frequent stimulant use (- 2.7, CI:-4.1;-1.4) compared to no or less frequent use. Females (1.8, CI:0.7;3.0) and participants with debt worries (2.2, CI:1.1;3.3) and unstable living conditions (1.7, CI:0.0;3.3) had also higher burden of mental health symptoms. There were large individual variations in SCL-10 score from baseline to follow-up, but no consistent time trends indicating change over time for the whole group. 65% of the cohort had a mean score > 1.85, the standard reference score.
conclusionsPeople with SUD have a considerable burden of mental health symptoms. We found no association between substance use patterns and change in mental health symptoms over time. This could suggest that the differences observed were indicating flattening of effects or self-medication to a larger degree than medication-related decline in mental health. This call for better individualized mental health assessment and patient care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.