ArticleRadiation oncology (London, England)2021
Dosimetric study between a single isocenter dynamic conformal arc therapy technique and Gamma Knife radiosurgery for multiple brain metastases treatment: impact of target volume geometrical characteristics.
Article in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Pooled it
- Article
- Dual optimization in single-isocenter radiosurgery for multiple brain metastases: a dosimetric planning study.Frontiers in oncology · 2026Article
- Article
- Decision-making between DCA and VMAT in Linac-based SRS for brain lesions: A dosimetric analysis based on tumor size and geometry and introduction of Qasym.Journal of applied clinical medical physics · 2025Article
- Dosimetric comparison of gamma knife and linear accelerator (VMAT and IMRT) plans of SBRT of Lung tumours.Scientific reports · 2024Article
- Impact of setup errors on the robustness of linac-based single-isocenter coplanar and non-coplanar VMAT plans for multiple brain metastases.Journal of applied clinical medical physics · 2024Article
- A high-resolution large-area detector for quality assurance in radiotherapy.Scientific reports · 2024Article
- Article
- Comparative study of dynamic conformal arc therapy and volumetric modulated arc therapy for treating single brain metastases: A retrospective analysis of dosimetric and clinical outcomes.Physics and imaging in radiation oncology · 2024Article
- Single isocenter dynamic conformal arcs-based radiosurgery for brain metastases: Dosimetric comparison with Cyberknife and clinical investigation.Technical innovations & patient support in radiation oncology · 2024Article
- Impact of MLC error on dose distribution in SRS treatment of single-isocenter multiple brain metastases: comparison between DCAT and VMAT techniques.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024Article
- Article
- Stereotactic Radiosurgery of Multiple Brain Metastases: A Review of Treatment Techniques.Cancers · 2023Review
- Planning issues on linac-based stereotactic radiotherapy.World journal of clinical cases · 2022Review
- A Comprehensive Evaluation of Single Isocenter Multiple Target SRS Plans and the Analytical Relationship between Plan Quality Indices with the Number and Volume of Targets.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Whole Brain Irradiation or Stereotactic RadioSurgery for five or more brain metastases (WHOBI-STER): A prospective comparative study of neurocognitive outcomes, level of autonomy in daily activities and quality of life.Clinical and translational radiation oncology · 2022Article
- Radiotherapy in Current Neuro-Oncology: There Is Still Much to Reveal.Life (Basel, Switzerland) · 2021Article
- Treatment of multiple intracranial metastases in radiation oncology: a contemporary review of available technologies.BJR open · 2021Review
- Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare linac-based mono-isocentric radiosurgery with Brainlab Elements Multiple Brain Mets (MBM) SRS and the Gamma Knife using a specific statistical method and to analyze the dosimetric impact of the target volume geometric characteristics. A dose fall-off analysis allowed to evaluate the Gradient Index relevancy for the dose spillage characterization. MATERIAL AND
methodsTreatments were planned on twenty patients with three to nine brain metastases with MBM 2.0 and GammaPlan 11.0. Ninety-five metastases ranging from 0.02 to 9.61 cc were included. Paddick Index (PI), Gradient Index (GI), dose fall-off, volume of healthy brain receiving more than 12 Gy (V
resultsFor mono-isocentric linac-based radiosurgery, the IDL around 70-75% was the best compromise found. For both techniques, the GI and the dose fall-off decreased with the target volume. In comparison, PI was slightly improved with MBM for targets < 1 cc or SI > 0.78. GI was improved with GP for targets < 2.5 cc. The V
conclusionsThe dose fall-off and the V
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.