ArticleBMC nephrology2021
The cumulative impact of social determinants of health factors on mortality in adults with diabetes and chronic kidney disease.
Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Food insecurity and kidney disease: a systematic review.International urology and nephrology · 2024Pooled it
- Polysocial risk score predicts chronic kidney disease incidence and prognosis: mechanistic insights from plasma metabolome, proteome and lifestyle.Science China. Life sciences · 2026Article
- Advancing Social Determinants Research in Prediabetes: Using Interpretable Statistical Models for Clinicians and Health Systems.Journal of general internal medicine · 2026Article
- Social Risk Factors and Disparities in Advanced Cardiovascular-Kidney-Metabolic Syndrome.JAMA network open · 2026Article
- Food and Nutrition Insecurity in Kidney Disease: Practitioner Considerations.Clinical journal of the American Society of Nephrology : CJASN · 2026Review
- Estimating Short-Term and Long-Term Survival for Patients With Kidney Failure Using a Mixture Survival Model.Kidney medicine · 2026Article
- Differential Effects of Social Determinants of Health Factors on Mortality in US Adults with Prediabetes: National Health and Nutrition Examination Survey 2005-2018.Journal of general internal medicine · 2026Article
- Article
- Social determinants of health and all-cause or cardiovascular mortality in chronic kidney disease: insights from 1999-2018 US National Health and Nutrition Examination Survey.Renal failure · 2025Article
- Social risk profiles and diabetic kidney disease: prevalence and mortality in US adults.BMC public health · 2025Article
- Integrated analysis identifies key genes underlying the bidirectional association between depression and renal failure.Scientific reports · 2025Article
- Social determinants of health and chronic kidney disease in United States adults: A cross-sectional study from National Health and Nutrition Examination Survey 2003-2018.Preventive medicine reports · 2025Article
- Explainable machine learning model incorporating social determinants of health to predict chronic kidney disease in type 2 diabetes patients.Journal of diabetes and metabolic disorders · 2025Article
- National cultural characteristics as defined by Hofstede's dimensions and their associations with population health.BMC public health · 2025Article
- Association between the life's essential 8 health behaviors score and all-cause mortality in cardiovascular-kidney-metabolic syndrome patients.Frontiers in nutrition · 2025Article
- Dose-dependent association between estimated glomerular filtration rate and the subsequent risk of depression: An analysis of a nationwide epidemiological dataset.European journal of clinical investigation · 2025Article
- Financial Toxicity and Kidney Disease in Children and Adults: A Scoping Review.International journal of nephrology and renovascular disease · 2025Review
- The impact of social determinants of health on chronic kidney disease risk: evidence from the CHARLS study.Frontiers in public health · 2025Article
- Prevalence of Cardiovascular-Kidney-Metabolic Syndrome Stages by Social Determinants of Health.JAMA network open · 2024 · on this mapArticle
- Association of Neighborhood Social Determinants of Health with Acute Kidney Injury during Hospitalization.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
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5 authors.
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Abstract
backgroundA growing body of evidence supports the potential role of social determinants of health on health outcomes. However, few studies have examined the cumulative effect of social determinants of health on health outcomes in adults with chronic kidney disease (CKD) with or without diabetes. This study examined the cumulative impact of social determinants of health on mortality in U.S. adults with CKD and diabetes.
methodsWe analyzed data from National Health and Nutrition Examination Surveys (2005-2014) for 1376 adults age 20 and older (representing 7,579,967 U.S. adults) with CKD and diabetes. The primary outcome was all-cause mortality. CKD was based on estimated glomerular filtration rate and albuminuria. Diabetes was based on self-report or Hemoglobin A1c of ≥6.5%. Social determinants of health measures included family income to poverty ratio level, depression based on PHQ-9 score and food insecurity based on Food Security Survey Module. A dichotomous social determinant measure (absence vs presence of ≥1 adverse social determinants) and a cumulative social determinant score ranging from 0 to 3 was constructed based on all three measures. Cox proportional models were used to estimate the association between social determinants of health factors and mortality while controlling for covariates.
resultsCumulative and dichotomous social determinants of health score were significantly associated with mortality after adjusting for demographics, lifestyle variables, glycemic control and comorbidities (HR = 1.41, 95%CI 1.18-1.68 and HR = 1.41, 95%CI 1.08-1.84, respectively). When investigating social determinants of health variables separately, after adjusting for covariates, depression (HR = 1.52, 95%CI 1.10-1.83) was significantly and independently associated with mortality, however, poverty and food insecurity were not statistically significant.
conclusionsSpecific social determinants of health factors such as depression increase mortality in adults with chronic kidney disease and diabetes. Our findings suggest that interventions are needed to address adverse determinants of health in this population.
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