ArticleBMC nephrology2021
SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report.
Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- A case report of concomitant anti-glomerular basement membrane disease, IgA nephropathy, and membranous nephropathy.BMC nephrology · 2026Article
- Clinical and pathological features of patients with recurrent anti-glomerular basement membrane disease.Renal failure · 2025Review
- Management dilemma of anti-GBM disease and p-ANCA-associated vasculitis with necrotizing skin lesions in a pediatric patient.Pediatric nephrology (Berlin, Germany) · 2025Article
- Crescentic Glomerulonephritis Possibly Caused by COVID-19 Infection.Journal of clinical medicine · 2025Article
- Case Report: Anti-glomerular basement membrane disease following COVID-19 infection.Frontiers in nephrology · 2025Article
- Epidemiological changes in anti-glomerular basement membrane disease in Madrid in the context of the COVID-19 pandemic.Frontiers in nephrology · 2025Article
- Pathological Sequelae of SARS-CoV-2: A Review for Clinicians.The Yale journal of biology and medicine · 2024Review
- The Immunobiological Agents for Treatment of Antiglomerular Basement Membrane Disease.Medicina (Kaunas, Lithuania) · 2023Review
- Autoimmunity and Infection in Glomerular Disease.Microorganisms · 2023Review
- Anti-glomerular basement membrane glomerulonephritis following COVID-19 infection without clinically evident pneumonia.International urology and nephrology · 2023Article
- Incidence of anti-glomerular basement membrane disease during the COVID-19 pandemic.Clinical kidney journal · 2022Article
- Mechanisms of SARS-CoV-2 Infection-Induced Kidney Injury: A Literature Review.Frontiers in cellular and infection microbiology · 2022Review
- Epidemiology, Impact, and Management Strategies of Anti-Glomerular Basement Membrane Disease.International journal of nephrology and renovascular disease · 2022Review
- Current Understanding of Clinical Manifestations of COVID-19 in Glomerular Disease.Glomerular diseases · 2021Review
- Nephrotic syndrome and vasculitis following SARS-CoV-2 vaccine: true association or circumstantial?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Article
- Temporal Clustering of Antiglomerular Basement Membrane Disease in COVID-19 Pandemic: A Case Series.International journal of nephrology and renovascular disease · 2021Article
- Anti-glomerular basement membrane disease in children: can Sars-Cov-2 be a trigger?Jornal brasileiro de nefrologiaArticle
- Double Anti-neutrophil Cytoplasmic Antibody and Anti-glomerular Basement Membrane Antibody-positive Crescentic Glomerulonephritis, Following SARS-CoV-2 Infection.Indian journal of nephrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage. Recently, an association between COVID-19 and anti-glomerular basement membrane (anti-GBM) disease has been proposed. We report on a patient with recurrence of anti-GBM disease after SARS-CoV-2 infection. CASE PRESENTATION: The 31-year-old woman had a past medical history of anti-GBM disease, first diagnosed 11 years ago, and a first relapse 5 years ago. She was admitted with severe dyspnoea, haemoptysis, pulmonary infiltrates and acute on chronic kidney injury. A SARS-CoV-2 PCR was positive with a high cycle threshold. Anti-GBM autoantibodies were undetectable. A kidney biopsy revealed necrotising crescentic glomerulonephritis with linear deposits of IgG, IgM and C3 along the glomerular basement membrane, confirming a recurrence of anti-GBM disease. She was treated with steroids, plasma exchange and two doses of rituximab. Pulmonary disease resolved, but the patient remained dialysis-dependent. We propose that pulmonary involvement of COVID-19 caused exposure of alveolar basement membranes leading to the production of high avidity autoantibodies by long-lived plasma cells, resulting in severe pulmonary renal syndrome.
conclusionOur case supports the assumption of a possible association between COVID-19 and anti-GBM disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.