Evidence map›Paper›PMID 33639867›Full record

ArticleBMC neurology2021

CIDP mimics: a case series.

Orly Moshe-Lilie, Erik Ensrud, Thomas Ragole, Chahin Nizar, Diana Dimitrova, Chafic Karam

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Case Report: Application ofFrontiers in nuclear medicine · 2024
    Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Orly Moshe-LilieDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Erik EnsrudDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Thomas RagoleDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Chahin NizarDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Diana DimitrovaDepartment of Neurology, Oregon Health & Science University, Portland, OR, USA.
Chafic KaramDepartment of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St., 3 West Gates, Philadelphia, PA, 19104, USA. chafic.karam@pennmedicine.upenn.edu.
Oregon Health & Science University · USHospital of the University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report our experience with a group of patients referred for refractory CIDP who fulfilled "definite" electrodiagnostic EFNS criteria for CIDP but were found to have an alternate diagnosis.

methodsPatients who were seen between 2017 and 2019 for refractory CIDP that fulfilled "definite" electrodiagnostic ENFS criteria for CIDP, but had an alternate diagnosis, were included. Patients who correctly had CIDP, anti MAG neuropathy, or MMN with conduction block, were excluded from the study. Demographics, clinical and electrophysiological characteristics, pertinent workup, final alternate diagnoses, and outcomes were collected.

resultsSeven patients were included: POEMS (n = 5), CANOMAD (n = 1), and neurolymphomatosis (n = 1). Most patients reported neuropathic pain and leg swelling (n = 6) or significant weight loss (n = 4). All patients had a monoclonal protein, and most patients who were tested had an elevated VEGF and CSF cyto-albuminologic dissociation. Electrophysiology showed pronounced intermediate more than distal demyelination, and axonal loss in the lower extremities. Response to steroids or IVIG varied, but some patients did respond to these treatments, especially early in the disease.

conclusionPain, systemic symptoms, suggestive electrophysiological findings, and/or a serum monoclonal protein should raise suspicion for CIDP mimics. Initial response to steroids or IVIG, over reliance on CSF, and electrophysiology findings can all be misleading.

Indexed as

AdultAgedAnemia, Hemolytic, AutoimmuneAtaxiaDiagnosis, DifferentialFemaleHumansMaleMiddle AgedNeurolymphomatosisOphthalmoplegiaPOEMS SyndromePolyradiculoneuropathy, Chronic Inflammatory DemyelinatingRetrospective StudiesCANOMADCIDPCIDP mimicsNeurolymphomatosisPOEMS

Identifiers

PMID33639867
PMCPMC7916267
OpenAlexW3134708311

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.