Evidence map›Paper›PMID 33639163›Full record

ArticleThe Journal of biological chemistry

Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport.

Maria Vistrup-Parry, W Bruce Sneddon, Sofie Bach, Kristian Strømgaard, Peter A Friedman, Tatyana Mamonova

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Intricacies of Renal Phosphate Reabsorption-An Overview.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maria Vistrup-ParryCenter for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
W Bruce SneddonLaboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Sofie BachCenter for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Kristian StrømgaardCenter for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Peter A FriedmanLaboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Tatyana MamonovaLaboratory for GPCR Biology, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: tbm7@pitt.edu.
University of Copenhagen · DKUniversity of Pittsburgh · US

Funding

Hormonal Regulation of NHERF1 in BoneR01DK105811 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, PETER A · 2016 to 2019
$2.5M
Functional Polarity of PTH Receptor Signaling: Cellular and Molecular MechanismsR01DK111427 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, PETER A, VILARDAGA, JEAN-PIERRE · 2017 to 2020
$2.4M
NIDDK NIH HHS R01 DK105811NIDDK NIH HHS R01 DK111427
6 · The paper itself

Abstract

The type II sodium-dependent phosphate cotransporter (NPT2A) mediates renal phosphate uptake. The NPT2A is regulated by parathyroid hormone (PTH) and fibroblast growth factor 23, which requires Na

Indexed as

Biological TransportFibroblast Growth Factor-23Fibroblast Growth FactorsG-Protein-Coupled Receptor KinasesHumansIon TransportMolecular Dynamics SimulationParathyroid HormonePDZ DomainsPhosphatesPhosphoproteinsPhosphorylationProtein BindingProtein ConformationSodium-Hydrogen ExchangersSodium-Phosphate Cotransporter Proteins, Type IIaFibroblast Growth Factor-23Fibroblast Growth FactorsG-protein-coupled receptor kinase 6G-Protein-Coupled Receptor KinasesParathyroid HormonePhosphatesPhosphoproteinsSLC34A1 protein, humansodium-hydrogen exchanger regulatory factorSodium-Hydrogen ExchangersSodium-Phosphate Cotransporter Proteins, Type IIabinding affinityG protein–coupled receptor kinase 6A (GRK6A)parathyroid hormone (PTH)PDZ domainPDZ-ligand interactionphosphate transportsimulation

Identifiers

PMID33639163
PMCPMC8042174
OpenAlexW3132920459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.