Evidence map›Paper›PMID 33639159›Full record

ArticleThe Journal of biological chemistry

Ca

Ryan Mahling, Cade R Rahlf, Samuel C Hansen, Matthew R Hayden, Madeline A Shea

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Calcium interaction with Nav1.5 via FGF12A and CaM binding.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Assessing the Role of Calmodulin's Linker Flexibility in Target Binding.International journal of molecular sciences · 2021
    Article
  10. NaThe Journal of biological chemistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ryan MahlingDepartment of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Cade R RahlfDepartment of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Samuel C HansenDepartment of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Matthew R HaydenDepartment of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Madeline A SheaDepartment of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA. Electronic address: madeline-shea@uiowa.edu.
University of Iowa · US

Funding

Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
MOLECULAR DISSECTION OF CALMODULIN DOMAIN INTERACTIONSR01GM057001 · NIGMS · UNIVERSITY OF IOWA · PI SHEA, MADELINE A · 1998 to 2015
$2.9M
NIGMS NIH HHS R01 GM057001NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

Voltage-gated sodium channels (Na

Indexed as

Amino Acid SequenceBinding SitesCalciumCalmodulinEF Hand MotifsFibroblast Growth FactorsHumansModels, MolecularNAV1.2 Voltage-Gated Sodium ChannelNuclear Magnetic Resonance, BiomolecularProtein BindingProtein Interaction Domains and MotifsVoltage-Gated Sodium ChannelsCalciumCalmodulinFGF12 protein, humanFibroblast Growth FactorsNAV1.2 Voltage-Gated Sodium ChannelVoltage-Gated Sodium ChannelsaffinityallosterybiosensorCa(2+)-dependent interactionFHFFRETmolecular recognitionNMRprotein–protein interactionthermodynamicsvoltage-gated sodium channel

Identifiers

PMID33639159
PMCPMC8059062
OpenAlexW3131477119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.