Evidence map›Paper›PMID 33638910›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2021

Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE

Daniel Vest Christophersen, Peter Møller, Morten Baekgaard Thomsen, Jens Lykkesfeldt, Steffen Loft, Håkan Wallin, Ulla Vogel, Nicklas Raun Jacobsen

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  10. Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoEFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Daniel Vest ChristophersenDepartment of Public Health, Section of Environmental Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen K, Denmark.
Peter MøllerDepartment of Public Health, Section of Environmental Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen K, Denmark.
Morten Baekgaard ThomsenDepartment of Biomedical Sciences, Heart and Circulatory Research Section, Faculty of Health Sciences, University of Copenhagen, Copenhagen N, Denmark.
Jens LykkesfeldtDepartment of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Steffen LoftDepartment of Public Health, Section of Environmental Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen K, Denmark.
Håkan WallinDepartment of Public Health, Section of Environmental Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen K, Denmark.
Ulla VogelThe National Research Centre for the Working Environment, Copenhagen, Denmark.
Nicklas Raun JacobsenThe National Research Centre for the Working Environment, Copenhagen, Denmark.ORCID 0000-0002-2504-2229
University of Copenhagen · DKNational Research Centre for the Working Environment · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway exposure to eg particulate matter is associated with cardiovascular disease including atherosclerosis. Acute phase genes, especially Serum Amyloid A3 (Saa3), are highly expressed in the lung following pulmonary exposure to particles. We aimed to investigate whether the human acute phase protein SAA (a homolog to mouse SAA3) accelerated atherosclerotic plaque progression in Apolipoprotein E knockout (ApoE

Indexed as

AnimalsAorta, ThoracicApolipoproteins EAtherosclerosisFemaleLipidsLungMalondialdehydeMiceMice, Inbred C57BLOxidative StressSerum Amyloid A ProteinApolipoproteins ELipidsMalondialdehydeSerum Amyloid A Proteinacute phase responseApolipoprotein E knockout (ApoE−/−) miceischemic heart diseaserecombinant human apolipoprotein serum amyloid A (hApo-SAA)Western-type diet

Identifiers

PMID33638910
PMCPMC12266322
OpenAlexW3133411730

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.