Evidence map›Paper›PMID 33638870›Full record

Observational studyActa anaesthesiologica Scandinavica2021

Cardiac arrhythmias in critically ill patients with coronavirus disease 2019: A retrospective population-based cohort study.

Mik Wetterslev, Peter Karl Jacobsen, Christian Hassager, Christian Jøns, Niels Risum, Steen Pehrson, Anders Bastiansen, Anne Sofie Andreasen, Klaus Tjelle Kristiansen, Morten H Bestle and 3 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Acta anaesthesiologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Effects of COVID-19 on Arrhythmia.Journal of cardiovascular development and disease · 2022
    Review
  10. The impact of Covid-19 on cardiovascular health.Nursing in critical care · 2022
    Article
  11. Review
  12. Cardiovascular System during SARS-CoV-2 Infection.International journal of environmental research and public health · 2022
    Review
  13. Article
  14. Observational
  15. Review
  16. Incidence and Clinical Outcomes of New-Onset Atrial Fibrillation in Critically lll Patients with COVID-19: A Multicenter Cohort Study - New-Onset Atrial Fibrillation and COVID-19.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Mik WetterslevDepartment of Intensive Care, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8798-1133
Peter Karl JacobsenDepartment of Cardiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Christian HassagerDepartment of Cardiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Christian JønsDepartment of Cardiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Niels RisumDepartment of Cardiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Steen PehrsonDepartment of Cardiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Anders BastiansenDepartment of Anaesthesia and Intensive Care, Bispebjerg Hospital and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Anne Sofie AndreasenDepartment of Anaesthesia and Intensive Care, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Klaus Tjelle KristiansenDepartment of Anaesthesia and Intensive Care, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Morten H BestleDepartment of Anaesthesia and Intensive Care, Nordsjaellands Hospital, University of Copenhagen, Copenhagen, Denmark.
Thomas MohrDepartment of Anaesthesia and Intensive Care, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Hasse Møller-SørensenDepartment of Cardiothoracic Anaesthesiology, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.
Anders PernerDepartment of Intensive Care, Rigshospitalet University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-4668-0123
University of Copenhagen · DK

Funding

Research Council of Rigshospitalet
6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) may be associated with cardiac arrhythmias in hospitalized patients, but data from the ICU setting are limited. We aimed to describe the epidemiology of cardiac arrhythmias in ICU patients with COVID-19.

methodsWe conducted a multicenter, retrospective cohort study including all ICU patients with an airway sample positive for severe acute respiratory syndrome corona-virus 2 from March 1st to June 1st in the Capital Region of Denmark (1.8 million inhabitants). We registered cardiac arrhythmias in ICU, potential risk factors, interventions used in ICU and outcomes.

resultsFrom the seven ICUs we included 155 patients with COVID-19. The incidence of cardiac arrhythmias in the ICU was 57/155 (37%, 95% confidence interval 30-45), and 39/57 (68%) of these patients had this as new-onset arrhythmia. Previous history of tachyarrhythmias and higher disease severity at ICU admission were associated with cardiac arrhythmias in the adjusted analysis. Fifty-four of the 57 (95%) patients had supraventricular origin of the arrhythmia, 39/57 (68%) received at least one intervention against arrhythmia (eg amiodarone, IV fluid or magnesium) and 38/57 (67%) had recurrent episodes of arrhythmia in ICU. Patients with arrhythmias in ICU had higher 60-day mortality (63%) as compared to those without arrhythmias (39%).

conclusionNew-onset supraventricular arrhythmias were frequent in ICU patients with COVID-19 and were related to previous history of tachyarrhythmias and severity of the acute disease. The mortality was high in these patients despite the frequent use of interventions against arrhythmias.

Indexed as

Critical IllnessSARS-CoV-2AgedArrhythmias, CardiacComorbidityCOVID-19DenmarkDiabetes MellitusDisease SusceptibilityFemaleHospital MortalityHumansHypertensionIncidenceIntensive Care UnitsMaleatrial fibrillationcardiac arrhythmiasCOVID-19critical illnessICU

Identifiers

PMID33638870
PMCPMC8014528
OpenAlexW3129242876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.