Evidence map›Paper›PMID 33638799›Full record

ArticleRice (New York, N.Y.)2021

Combination of High Zn Density and Low Phytic Acid for Improving Zn Bioavailability in Rice (Oryza stavia L.) Grain.

Yin Wang, Yusha Meng, Yanping Ma, Lei Liu, Dianxing Wu, Xiaoli Shu, Liqing Pan, Qixian Lai

Open access · goldAbstract read
In one paragraph

Article in Rice (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yin WangInstitute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China. wangyin@zaas.ac.cn.ORCID http://orcid.org/0000-0001-8384-6789
Yusha MengInstitute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Yanping MaInstitute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Lei LiuInstitute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
Dianxing WuState Key Laboratory of Rice Biology, Institute of Nuclear Agriculture Sciences, Zhejiang University, Hangzhou, 310029, China.
Xiaoli ShuState Key Laboratory of Rice Biology, Institute of Nuclear Agriculture Sciences, Zhejiang University, Hangzhou, 310029, China.
Liqing PanYuyao County Agricultural Techniques Promotion and Service Station, Yuyao Agricultural and Rural Bureau, Ningbo, 315400, China.
Qixian LaiInstitute of Rural Development, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
ZheJiang Academy of Agricultural Sciences · CNChina National Rice Research Institute · CN

Funding

Science and Technology Program of Zhejiang Province of China 2018C02057Youth Training Program of Zhejiang Academy of Agricultural Sciences of China 2020R18R08E02
6 · The paper itself

Abstract

backgroundZn deficiency is one of the leading public health problems in the world. Staple food crop, such as rice, cannot provide enough Zn to meet the daily dietary requirement because Zn in grain would chelate with phytic acid, which resulted in low Zn bioavailability. Breeding new rice varieties with high Zn bioavailability will be an effective, economic and sustainable strategy to alleviate human Zn deficiency.

resultsThe high Zn density mutant LLZ was crossed with the low phytic acid mutant Os-lpa-XS110-1, and the contents of Zn and phytic acid in the brown rice were determined for the resulting progenies grown at different sites. Among the hybrid progenies, the double mutant always displayed significantly higher Zn content and lower phytic acid content in grain, leading to the lowest molar ratio of phytic acid to Zn under all environments. As assessed by in vitro digestion/Caco-2 cell model, the double mutant contained the relatively high content of bioavailable Zn in brown rice.

conclusionsOur findings suggested pyramiding breeding by a combination of high Zn density and low phytic acid is a practical and useful approach to improve Zn bioavailability in rice grain.

Indexed as

BioavailabilityBiofortificationCross-breedingRiceZinc (Zn)

Identifiers

PMID33638799
PMCPMC7914331
OpenAlexW3131030779

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.