Evidence map›Paper›PMID 33638692›Full record

ArticleNeuroradiology2021

MR vessel wall imaging in tubercular meningitis.

Neha Choudhary, Sameer Vyas, Manish Modi, Shashank Raj, Ajay Kumar, Naveen Sankhyan, Renu Suthar, Arushi Gahlot Saini, Manoj Kumar Goyal, Chirag Kamal Ahuja and 1 more

Abstract read
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In one paragraph

Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  13. Detection of meningovascular neurotuberculosis through intracranial vessel wall imaging.Revista da Sociedade Brasileira de Medicina Tropical · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Neha ChoudharyDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Sameer VyasDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India. sameer574@yahoo.co.in.ORCID http://orcid.org/0000-0002-0113-0486
Manish ModiDepartment of Neurology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Shashank RajDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Ajay KumarDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Naveen SankhyanDepartment of Pediatric Neurology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Renu SutharDepartment of Pediatric Neurology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Arushi Gahlot SainiDepartment of Pediatric Neurology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Manoj Kumar GoyalDepartment of Neurology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Chirag Kamal AhujaDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Paramjeet SinghDepartment of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/PR23178/MED/29/1183/2017
6 · The paper itself

Abstract

purposeTubercular meningitis (TBM) has the propensity to cause secondary vasculitis through various mechanisms leading to development of cerebrovascular complications. These vascular involvements can be detected by vessel wall imaging (VWI). In this study, we aimed to study detailed findings of vessel wall imaging in cases of tubercular meningitis.

methodsAll consecutive patients of suspected tubercular meningitis in whom diagnosis of TBM could be made according to diagnostic criteria given by Ahuja et al. were included in the study. High-resolution MR VWI and time of flight (TOF) magnetic resonance angiography (MRA) were done along with routine MRI sequences. Arteries up to second-order branches were studied, and statistical analyses were done with respect to stage of tubercular meningitis, infarctions and TOF MRA findings.

resultsOut of all 101 cases of TBM, infarctions were found in 49 cases (48.5%), and vessel wall enhancement was seen in 67 cases (66.3%). With increasing severity of disease, more severe vascular involvement was seen on VWI. There was significant association between enhancement of individual arteries and infarctions in their territories. VWI had better sensitivity than the MRA, while MRA had better specificity than VWI for detection of vascular complications.

conclusionTubercular vasculitis can be detected by VWI in the form of nodular or smooth segmental enhancement of vessel wall with or without stenosis. Incorporation of VWI in routine MR imaging can play a greater role in early detection and management of cerebrovascular complications which can help to improve prognosis of the disease.

Indexed as

Tuberculosis, MeningealArteriesConstriction, PathologicHumansMagnetic Resonance AngiographyMagnetic Resonance ImagingMRITubercular meningitisVessel wall imaging

Identifiers

PMID33638692
OpenAlexW3131547187

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.