Evidence map›Paper›PMID 33638633›Full record

ArticleJournal of the National Cancer Institute2021

Measuring Self-Reported Cancer-Related Cognitive Impairment: Recommendations From the Cancer Neuroscience Initiative Working Group.

Ashley M Henneghan, Kathleen Van Dyk, Tara Kaufmann, Rebecca Harrison, Christopher Gibbons, Cobi Heijnen, Shelli R Kesler

Erratum issued Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06103318 (Cognitive Rehabilitation and Psychosocial Intervention Through a Stepped Digital Ecosystem in Breast Cancer), which is not on this map. Cited by 70 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 8 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06103318 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Cognitive Rehabilitation and Psychosocial Intervention Through a Stepped Digital Ecosystem in Breast Cancer: A Randomized Clinical Trial.

TypeinterventionalSponsorInstitut Català d'OncologiaRan2024 to 2025Enrolled176ConditionsBreast Cancer, Cognitive DysfunctionArmsICOgnition
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 8 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Cancer-related cognitive impairment in patients with hematologic malignancies after CAR T cell therapy: a systematic review and meta-analysis of prevalence.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  5. Self- and informant-reported cognitive concerns associated with primary brain tumour: systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Prevalence and assessment tools of cancer-related cognitive impairment in lung cancer survivors: a systematic review and proportional meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  9. Trial
  10. Article
  11. Methodology of analysis of cognitive impairment in longitudinal randomized clinical trials in oncology: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  12. Cancer-related cognitive impairment in adult cancer survivors: a clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  13. Article
  14. Accounting for unmet needs resulting from cancer-related cognitive impairment.Journal of cancer survivorship : research and practice · 2026
    Article
  15. Article
  16. Work challenges and cancer-related cognitive impairment: level of education accounts for unmet needs beyond cognitive impairment severity.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  17. Review
  18. Cognitive impairment is associated with altered blood cell profiles in aggressive lymphoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ashley M HenneghanSchool of Nursing, University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-6733-1926
Kathleen Van DykSemel Institute, Department of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, USA.ORCID 0000-0003-1500-930X
Tara KaufmannDepartment of Oncology , Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Rebecca HarrisonDepartment of Neuro Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-5689-8492
Christopher GibbonsDepartment of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cobi HeijnenDepartment of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-1928-3050
Shelli R KeslerSchool of Nursing, Department of Diagnostic Medicine, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
The University of Texas at Austin · USThe University of Texas MD Anderson Cancer Center · USUCLA Jonsson Comprehensive Cancer Center

Funding

OLDER BREAST CANCER PATIENTS: RISK FOR COGNITIVE DECLINER01CA129769 · NCI · GEORGETOWN UNIVERSITY · PI AHLES, TIM ALAN, MANDELBLATT, JEANNE · 2009 to 2020
$7.3M
Bio-behavioral Research At The Intersection of Cancer and AgingR35CA197289 · NCI · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE · 2015 to 2021
$6.2M
Very-long Term Neurocognitive Outcomes in Breast Cancer Survivors (ProbC2)R01CA172145 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI KESLER, SHELLI R, PALESH, OXANA G · 2012 to 2024
$3.3M
Predicting Long-Term Chemotherapy-Related Cognitive ImpairmentR01CA226080 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI KESLER, SHELLI R, PALESH, OXANA G · 2019 to 2024
$3.1M
Cognitive Aging, Alzheimers disease, and Cancer-related Cognitive DeclineR01AG068193 · NIA · GEORGETOWN UNIVERSITY · PI MANDELBLATT, JEANNE, SAYKIN, ANDREW J · 2020 to 2023
$2.8M
Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine TherapyK08CA241337 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DYK, KATHLEEN · 2019 to 2023
$925k
Brain Connectivity and Self-Reported Cancer Related Cognitive ImpairmentK01NR018970 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI HENNEGHAN, ASHLEY M. · 2020 to 2022
$312k
NCI NIH HHS K08 CA241337NCI NIH HHS R01 CA129769NCI NIH HHS R01 CA172145NCI NIH HHS R01 CA226080NCI NIH HHS R35 CA197289NIA NIH HHS R01 AG068193NINR NIH HHS K01 NR018970
6 · The paper itself

Abstract

Cancer and its treatments are associated with increased risk for cancer-related cognitive impairment (CRCI). Methods and measures used to study and assess self-reported CRCI (sr-CRCI), however, remain diverse, resulting in heterogeneity across studies. The Patient-Reported Outcomes Working Group has been formed to promote homogeneity in the methods used to study sr-CRCI. In this report, using a psychometric taxonomy, we inventory and appraise instruments used in research to measure sr-CRCI, and we consider advances in patient-reported outcome methodology. Given its psychometric properties, we recommend the Patient-Reported Outcome Measurement Information System Cognitive Function Short Form 8a for measurement of sr-CRCI in cancer patients and survivors, at a minimum, to increase scientific rigor and progress in addressing CRCI.

Indexed as

Cognitive DysfunctionNeoplasmsCognitionHumansSelf Report

Identifiers

PMID33638633
PMCPMC8849125
OpenAlexW3130029022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.