Evidence map›Paper›PMID 33638034›Full record

ReviewInternational journal of hematology2021

Liver transplantation for congenital protein C deficiency with initial poor graft function: a case report with literature review.

Atsushi Sakamoto, Akira Ishiguro, Akinari Fukuda, Seisuke Sakamoto, So-Ichi Suenobu, Tomoko Matsumoto, Keiji Nogami, Shouichi Ohga, Mureo Kasahara

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in International journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Atsushi SakamotoCenter for Postgraduate Education and Training, National Center for Child Health and Development (NCCHD), Tokyo, Japan.
Akira IshiguroCenter for Postgraduate Education and Training, National Center for Child Health and Development (NCCHD), Tokyo, Japan. ishiguro-a@ncchd.go.jp.ORCID http://orcid.org/0000-0002-3896-5313
Akinari FukudaOrgan Transplantation Center, NCCHD, Tokyo, Japan.
Seisuke SakamotoOrgan Transplantation Center, NCCHD, Tokyo, Japan.
So-Ichi SuenobuDepartment of Pediatrics, Oita University, Oita, Japan.
Tomoko MatsumotoDepartment of Pediatrics, Nara Medical University, Nara, Japan.
Keiji NogamiDepartment of Pediatrics, Nara Medical University, Nara, Japan.
Shouichi OhgaDepartment of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Mureo KasaharaOrgan Transplantation Center, NCCHD, Tokyo, Japan.
National Center For Child Health and Development · JPNara Medical University · JPKyushu University · JPOita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital deficiency of protein C (PC) is a rare disease that causes thrombophilia during the neonatal and infantile periods. Despite anticoagulative treatments, purpura fulminans and major vessel thrombosis often occur. We report a 7-year-old girl with congenital PC deficiency who underwent deceased donor liver transplantation (LT) and experienced complications accompanied by initial poor graft function (IPGF). Before LT, she had cerebral and ophthalmic hemorrhage, and seven episodes of purpura fulminans. The operation was successfully performed; however, the liver graft developed IPGF. Hyperammonemia and coagulopathy required continuous hemodiafiltration and infusion of fresh frozen plasma. It took 22 days for PC activity to reach reference levels. The changes in clotting and anticlotting activities in the patient's plasma were revealed using clot waveform analysis and the HemosIL ThromboPath

Indexed as

Liver TransplantationBlood CoagulationChildFemaleHemodiafiltrationHumansLiverProtein C DeficiencyTransplantsCongenital deficiencyDeceased donorInitial poor graft functionLiver transplantationProtein C

Identifiers

PMID33638034
OpenAlexW3129691277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.