Evidence map›Paper›PMID 33637964›Full record

ArticleCommunications biology2021

Specific PIP

Zhiguang Jia, Jianhan Chen

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

  1. Pacemaking in the lymphatic system.The Journal of physiology · 2026
    Review
  2. Review
  3. Allosteric coupling between PIPProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Calcium-activated chloride channel TMEM16A opens via pi-helical transition in transmembrane segment 4.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Distinct modulation of calcium-activated chloride channel TMEM16A by drug-binding sites.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Niclosamide potentiates TMEM16A and induces vasoconstriction.The Journal of general physiology · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zhiguang JiaDepartment of Chemistry, University of Massachusetts, Amherst, MA, USA.
Jianhan ChenDepartment of Chemistry, University of Massachusetts, Amherst, MA, USA. jianhanc@umass.edu.ORCID 0000-0002-5281-1150
University of Massachusetts Amherst · US

Funding

Mechanism of BK Channel GatingR01HL142301 · NHLBI · WASHINGTON UNIVERSITY · PI SILVA, JONATHAN R · 2018 to 2021
$2.9M
Disordered Proteins and Dynamic Interactions in Biology and Diseases.R35GM144045 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jianhan Chen · 2022 to 2026
$2.0M
NIGMS NIH HHS R35 GM144045
6 · The paper itself

Abstract

TMEM16A is a widely expressed Ca

Indexed as

Ion Channel GatingAnimalsAnoctamin-1Binding SitesCalciumChloridesMiceMolecular Dynamics SimulationPhosphatidylinositol 4,5-DiphosphateProtein BindingANO1 protein, mouseAnoctamin-1CalciumChloridesPhosphatidylinositol 4,5-Diphosphate

Identifiers

PMID33637964
PMCPMC7910439
OpenAlexW3130546020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.