ArticleScientific reports2021
Faecal bacterial composition in horses with and without free faecal liquid: a case control study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
- Serum physiology, fecal microbiota, and metabolome signatures associated with perinatal stage transitions in Mongolian mares.Frontiers in veterinary science · 2026Article
- Alterations in the Microbiome of Horses Affected with Fecal Water Syndrome.Veterinary sciences · 2025Article
- Dysbiosis not observed in Canadian horse with free fecal liquid (FFL) using 16S rRNA sequencing.Scientific reports · 2024Article
- Chemical composition and physical characteristics of faeces in horses with and without free faecal liquid - two case-control studies.BMC veterinary research · 2022Article
- Free Faecal Water: Analysis of Horse Faecal Microbiota and the Impact of Faecal Microbial Transplantation on Symptom Severity.Animals : an open access journal from MDPI · 2021Article
- Feeding and Management of Horses with and without Free Faecal Liquid: A Case-Control Study.Animals : an open access journal from MDPI · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Free faecal liquid (FFL) is a condition in horses which manifests as differential defecation of solid and liquid phases of faeces. The etiology of FFL is currently unknown, but deviances in the hindgut microbiota has been suggested to be of importance. The present study aimed to compare the faecal bacterial composition of farm-matched horses with (case, n = 50) and without (control, n = 50) FFL. Samples were collected at three different occasions. The V3 and V4 regions of the 16S rRNA gene were amplified and sequenced using Illumina sequencing. Also, samples were cultivated for detection of Clostridioides difficile and Clostridium perfringens. Analysis revealed similar faecal bacterial composition between case and control horses, but an effect of sampling period (p = 0.0001). Within sampling periods, 14 genera were present in higher or lower proportions in case compared to control horses in at least one sampling period. Compared to controls, case horses had higher relative abundance of Alloprevotella (adjusted p < 0.04) and lower relative abundance of Bacillus spp. (adjusted p < 0.03) in at least two sampling periods. All horses tested negative for C. difficile and C. perfringens by culture of faeces. Further studies are required to establish the clinical relevance of specific bacterial taxa in FFL.
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