Evidence map›Paper›PMID 33637679›Full record

ArticleSignal transduction and targeted therapy2021

SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies.

Yang Yang, Lanying Du

Abstract readComment
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Trial
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  6. Observational
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  14. Observational
  15. Decoding the cross-immune pressure: Dengue's role in SARS-CoV-2 evolution.Computational and structural biotechnology journal · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yang YangRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA.
Lanying DuLindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA. ldu@nybc.org.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Structure-based design of coronavirus subunit vaccinesR01AI139092 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING · 2018 to 2022
$4.2M
Rational design and evaluation of novel mRNA vaccines against MERS-CoVR01AI137472 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING · 2018 to 2022
$4.1M
Novel nanobodies to prevent and treat SARS-CoV-2 and other pathogenic human coronavirusesR01AI157975 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING, LI, FANG · 2020 to 2025
$3.9M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI137472NIAID NIH HHS R01 AI139092NIAID NIH HHS R01 AI157975U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01AI137472U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01AI139092U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01AI157975
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Spike Glycoprotein, CoronavirusAntibodies, NeutralizingHumansSARS-CoV-2Antibodies, NeutralizingSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID33637679
PMCPMC7908000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.