Evidence map›Paper›PMID 33637615›Full record

ArticleStroke and vascular neurology2021

Associations between haemodynamics and wall enhancement of intracranial aneurysm.

Miaoqi Zhang, Fei Peng, Xin Tong, Xin Feng, Yunduo Li, Huijun Chen, Hao Niu, Baorui Zhang, Guangrong Song, Youxiang Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in Stroke and vascular neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Miaoqi Zhang *Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.ORCID 0000-0003-4119-4940
Fei Peng *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xin Tong *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0002-4893-1299
Xin FengDepartment of Neurosurgery, Beijing Hospital, Beijing, China.
Yunduo LiCenter for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Huijun ChenCenter for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Hao NiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Baorui ZhangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Guangrong SongBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Youxiang LiBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Peng LiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Aihua Liu *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0002-6391-805X
Rui Li *Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China leerui@tsinghua.edu.cn.
Capital Medical University · CNTsinghua University · CNBeijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePrevious studies have reported about inflammation processes (IPs) that play important roles in aneurysm formation and rupture, which could be driven by blood flow. IPs can be identified using aneurysmal wall enhancement (AWE) on high-resolution black-blood MRI (BB-MRI) and blood flow haemodynamics can be demonstrated by four-dimensional-flow MRI (4D-flow MRI). Thus, this study investigated the associations between AWE and haemodynamics in unruptured intracranial aneurysms (IA) by combining 4D-flow MRI and high-resolution BB-MRI. MATERIALS AND

methodsBetween April 2014 and October 2017, 48 patients with 49 unruptured IA who underwent both 4D-flow MRI and high-resolution BB-MRI were retrospectively included in this study. The haemodynamic parameters demonstrated using 4D-flow MRI were compared between different AWE patterns using the Kruskal-Wallis test and ordinal regression.

resultsThe results of Kruskal-Wallis test showed that the average wall shear stress in the IA (WSS

conclusionA low WSS and low average vorticity were independently associated with a high AWE grade for IAs larger than 4 mm. Therefore, WSS and average vorticity could predict AWE and circumferential AWE.

Indexed as

Intracranial AneurysmHemodynamicsHumansMagnetic Resonance ImagingRetrospective StudiesStress, MechanicalaneurysminflammationMRIvessel wall

Identifiers

PMID33637615
PMCPMC8485248
OpenAlexW3130965132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.