Evidence map›Paper›PMID 33637586›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study.

Jaewon Yang, Luyao Shi, Rui Wang, Edward J Miller, Albert J Sinusas, Chi Liu, Grant T Gullberg, Youngho Seo

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. On Hallucinations in Artificial Intelligence-Generated Content for Nuclear Medicine Imaging (the DREAM Report).Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
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  13. Review
  14. Accurate and efficient rapid acquisition early post-injection stress-first CZT SPECT myocardial perfusion imaging with tetrofosmin and attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  15. The past, present, and future of attenuation correction for myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  16. Article
  17. Deep-learning-based methods of attenuation correction for SPECT and PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  18. Article
  19. Article
  20. Applying deep learning attenuation correction in the presence of motion.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jaewon YangPhysics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California; jaewon.yang@ucsf.edu.
Luyao ShiBiomedical Engineering, Yale University, New Haven, Connecticut.
Rui WangRadiology and Biomedical Imaging, Yale University, New Haven, Connecticut.
Edward J MillerRadiology and Biomedical Imaging, Yale University, New Haven, Connecticut.
Albert J SinusasBiomedical Engineering, Yale University, New Haven, Connecticut.
Chi LiuBiomedical Engineering, Yale University, New Haven, Connecticut.
Grant T GullbergPhysics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
Youngho SeoPhysics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
Yale University · USUniversity of California, San Francisco · USTsinghua University · CN

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Low-dose SPECT/CT for imaging chemotherapy-induced microvascular cardiotoxicityR01HL123949 · NHLBI · YALE UNIVERSITY · PI LIU, CHI · 2014 to 2018
$3.2M
Energy-independent single photon molecular imaging technologyR01EB026331 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CUI, YONGGANG, SEO, YOUNGHO · 2018 to 2022
$2.6M
Dynamic cardiac SPECTR01HL135490 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GULLBERG, GRANT T, SEO, YOUNGHO · 2017 to 2020
$2.4M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL123949NHLBI NIH HHS R01 HL135490NIBIB NIH HHS R01 EB026331
6 · The paper itself

Abstract

Dedicated cardiac SPECT scanners with cadmium-zinc-telluride cameras have shown capabilities for shortened scan times or reduced radiation doses, as well as improved image quality. Since most dedicated scanners do not have integrated CT, image quantification with attenuation correction (AC) is challenging and artifacts are routinely encountered in daily clinical practice. In this work, we demonstrated a direct AC technique using deep learning (DL) for myocardial perfusion imaging (MPI).

Indexed as

Deep LearningFeasibility StudiesHeartImage Processing, Computer-AssistedMyocardial Perfusion ImagingAgedArtifactsFemaleHumansMaleMiddle AgedRetrospective StudiesSingle Photon Emission Computed Tomography Computed TomographyTomography, Emission-Computed, Single-Photonattenuation correctioncardiac SPECTdeep learningMPI

Identifiers

PMID33637586
PMCPMC8612332
OpenAlexW3130521431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.