Evidence map›Paper›PMID 33637549›Full record

ArticleBMJ open2021

COVID-19 in a cohort of pregnant women and their descendants, the MOACC-19 study.

Javier Llorca, Carolina Lechosa-Muñiz, Pilar Gortazar, María Fernández-Ortiz, Yolanda Jubete, Maria J Cabero, MOACC-19 group

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Results of Pregnancy Control before and during the COVID-19 Pandemic: A Comparison of Two Cohorts.International journal of environmental research and public health · 2021
    Article
  5. Influence of Socioeconomic Status on SARS-CoV-2 Infection in Spanish Pregnant Women. The MOACC-19 Cohort.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Javier LlorcaUniversidad de Cantabria Facultad de Medicina, Santander, Cantabria, Spain javier.llorca@unican.es.ORCID 0000-0001-8569-861X
Carolina Lechosa-MuñizBreastfeeding Coordinator, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain.
Pilar GortazarUniversidad de Cantabria Facultad de Medicina, Santander, Cantabria, Spain.
María Fernández-OrtizInstituto de Investigación Sanitaria Valdecilla (IDIVAL), Santander, Cantabria, Spain.
Yolanda JubeteUniversidad de Cantabria Facultad de Medicina, Santander, Cantabria, Spain.
Maria J CaberoUniversidad de Cantabria Facultad de Medicina, Santander, Cantabria, Spain.
MOACC-19 group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Mother and Child COVID-19 study is a cohort recruiting pregnant women and their children in Cantabria, North of Spain, during COVID-19 pandemic in order to ascertain consequences of SARS-CoV-2 infection on pregnant women and their descendants. This article reports the cohort profile and preliminary results as recruitment is still open.

participantsThree subcohorts can be identified at recruitment. Subcohort 1 includes women giving birth between 23 March and 25 May 2020; they have been retrospectively recruited and could have been exposed to COVID-19 only in their third trimester of pregnancy. Subcohort 2 includes women giving birth from 26 May 2020 on; they are being prospectively recruited and could have been exposed to COVID-19 in both their second and third trimesters of pregnancy. Subcohort 3 includes women in their 12 week of pregnancy prospectively recruited from 26 May 2020 on; they could have been exposed to COVID-19 anytime in their pregnancy. All women are being tested for SARS-CoV-2 infection using both RT-PCR for RNA detection and ELISA for anti-SARS-CoV-2 antibodies. All neonates are being tested for antibodies using immunochemoluminiscency tests; if the mother is tested positive for SARS-CoV-2 RNA, a nasopharyngeal swab is also obtained from the child for RT-PCR analysis. FINDINGS TO DATE: As of 22 October, 1167 women have been recruited (266, 354 and 547 for subcohorts 1, 2 and 3, respectively). Fourteen women tested positive to SARS-CoV-2 RNA by the day of delivery. All 14 children born from these women tested negative for SARS-CoV-2 RNA. FUTURE PLANS: Children from women included in subcohort 3 are expected to be recruited by the end of 2020. Children will be followed-up for 1 year in order to ascertain the effect that COVID-19 on their development.

Indexed as

Infectious Disease Transmission, VerticalPregnancy Complications, InfectiousCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingFemaleHumansInfantInfant, NewbornPandemicsPregnancyProspective StudiesRetrospective StudiesRNA, ViralSARS-CoV-2SpainRNA, Viralepidemiologymaternal medicinepaediatric infectious disease & immunisationpublic health

Identifiers

PMID33637549
PMCPMC7918808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.