ArticleBMC pediatrics2021
Clinical profile and outcome of acute organophosphate poisoning in children of Upper Egypt: a cross-sectional study.
Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06447584 (Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital), which is not on this map. Cited by 19 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital
Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Toxidromes.Nature reviews. Disease primers · 2026Review
- Childhood and adolescent poisoning: a prospective analysis from the largest poison control centre.BMC pediatrics · 2026Article
- Current review on inducible nitric oxide synthase and Src tyrosine kinase inhibitors as disease-modifiers in preclinical models of epilepsy.Histology and histopathology · 2026Review
- Exposure to pesticides and renal function in agricultural workers in Rafsanjan, Iran: a case-control study.Journal of health, population, and nutrition · 2025Article
- Prospective cohort study on the characteristics of acute poisoning patients at a tertiary care hospital in Pakistan.BMJ open · 2025Article
- Current pesticide suicide surveillance methods used across the African continent: a scoping review.BMJ open · 2025Article
- Article
- Characteristics of 76,113 Acute Poisoning Cases Registered in Emergency Medical System of Tehran Province; A Cross-sectional Study.Archives of academic emergency medicine · 2025Article
- Factors Associated with the Development of Depression and the Influence of Obesity on Depressive Disorders: A Narrative Review.Biomedicines · 2024Review
- Validity of different scoring systems in prediction of intensive care unit admission and mortality in acute organophosphate poisoning.Toxicology research · 2024Article
- Article
- Acute Poisoning among Children Admitted in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2024Article
- Article
- Organophosphorus Poisoning: Acute Respiratory Distress Syndrome (ARDS) and Cardiac Failure as Cause of Death in Hospitalized Patients.International journal of molecular sciences · 2023Review
- Initial clinical and laboratory parameters triaging non-pharmaceutical acute pediatric poisoned patients for potential adverse outcomes: a three-year retrospective study.Toxicology research · 2023Article
- Pattern and outcome of acute organophosphate poisoning at health facilities of Harari Region, Eastern Ethiopia.SAGE open medicine · 2023Article
- Organophosphate Poisoning in a Paediatric Intensive Care Unit: A Retrospective Analysis Based on Ten Years of Experience.International journal of general medicine · 2022Article
- Characterization of Acute Poisoning in Hospitalized Children in Southwest China.Frontiers in pediatrics · 2021Article
- Successful treatment of intermediate syndrome in a COVID-19 patient with severe organophosphate toxicity.International journal of critical illness and injury scienceArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrganophosphates are one of the most common agents of poisoning in developing countries including Egypt. Due to lack of data about characteristics of organophosphates poisoning in our localities, we aimed to evaluate its clinical pattern and factors affecting outcome.
methodsIt was a cross-sectional study conducted in South valley University hospital between January 2019 and December 2019. It included all children ≤16 years of age presented with organophosphates poisoning. Diagnosis was performed from the history taken from the patient's relatives and presenting symptoms. Demographic data, mode and route of poisoning, time from exposure to presentation, clinical symptomatology, grading and routine investigations were evaluated in addition to treatment taken and outcome.
resultsDuring the study period, 108 children; mean age was 7.95 ± 4.11 years (range 1. 5-16 years) presented with organophosphorous poisoning. Sixty five (60%) cases were females and 43 (40%) were males. Unintentional acts (87%) were detected more than suicidal (13%) and inhalation route (63.8%) more than ingestion (36. 2%). Miosis was the most frequent clinical sign (100%) followed by respiratory distress (77.7%). Regarding time of presentation to emergency department, 43 (40%) cases were presented within 6 h while others presented more than 6 h post-exposure. Mechanical ventilation (MV) was needed for 14 (13%) cases and 6 (5.5%) cases died due to respiratory failure. Duration of hospital stay, mean time interval from toxic exposure to hospital presentation, leucocytosis, need for MV and cumulative dose of pralidoxime were significantly higher in non survivors than survivors while Pao2 (partial arterial oxygen) and GCS (Glasgow coma scale) were significantly lower.
conclusionThis study concluded that time consumed till presentation to hospital, low GCS, need for MV, leucocytosis, decreased PaO2 and increased cumulative dose of pralidoxime were independent risk factors of mortality.
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