ArticleBMC public health2021
Burden of cancers attributable to modifiable risk factors in Malaysia.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The landscape of adult obesity in Malaysia: a mapping of evidence and contemporary narrative review.The Lancet regional health. Western Pacific · 2026Review
- Global and regional cancer burden attributable to modifiable risk factors to inform prevention.Nature medicine · 2026Article
- The global landscape of cancer burden attributable to tobacco smoking in 2022: a population-based systematic analysis.EClinicalMedicine · 2026Article
- The Malaysian Burden of Disease Study: Protocol for Mortality, Morbidity, and Risk Factor Evaluation.JMIR research protocols · 2025Article
- Cancer Burden Across The South East Asia Nation (ASEAN) in 2022.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Cancer patients' willingness to trade time for health: factors that affect their decision.BMC public health · 2025Article
- Dosimetry Evaluation on the Use ofThe Malaysian journal of medical sciences : MJMS · 2025Article
- The Cancer Burden in Sarawak, Malaysia: Sarawak Cancer Report.Health science reports · 2025Article
- A Systematic Review: The Role of Artificial Intelligence in Lung Cancer Screening in Detecting Lung Nodules on Chest X-Rays.Diagnostics (Basel, Switzerland) · 2025Review
- Proportion of cancer cases and deaths attributable to potentially modifiable risk factors in Peru.BMC cancer · 2024Article
- Health status based on EQ-5D-5L for the cancer patient population in Malaysia.Scientific reports · 2024Article
- Challenges and Strategies for Improving Access to Cancer Drugs in Malaysia: Summary of Opinions Expressed at the 2nd MACR International Scientific Conference 2022.Cancer management and research · 2023Article
- Fighting Cancer around the World: A Framework for Action.Healthcare (Basel, Switzerland) · 2022Article
- Cancer incidence and mortality and risk factors in member countries of the " Belt and Road " initiative.BMC cancer · 2022Article
- Prediction of Productivity Costs Related to Cervical Cancer Mortality in Indonesia 2018.The Malaysian journal of medical sciences : MJMS · 2022Article
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2 authors.
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Abstract
backgroundThis is a systematic assessment of the burden of cancers in Malaysia in 2018 using epidemiologic approach. The purpose of this study was to identify the proportion of cancers in Malaysia that were attributable to the modifiable risk factors of excess weight, alcohol intake, physical inactivity, tobacco smoking and to estimate the number of cancer cases that could be prevented if the exposure to the modifiable risk factor was reduced.
methodsWe estimated the Population Attributable Fraction (PAF) of the modifiable risk factors to cancers incidences in Malaysia. The two parameters used for the estimation were exposure prevalence from national representative surveys and the relative risk of getting the cancers from worldwide literature review.
resultsAmong 38,426 cancer incidences in 2018 from Globocan data, we estimated that 22.2% (95% confidence interval (CI):14.9 to 29.6%) of the cancer incidences included in this study were attributable to the investigated modifiable risk factors. 39.1% (95% CI:27.2 to 49.7%) and 10.5% (95% CI:5.8 to 15.7%) of cancers in male and female respectively, were attributable to the studied modifiable risk factors. The top main cancers attributed by the risk factors were lung cancer (65.1%; 95% CI:56.4 to 72.9%), laryngeal cancer (63.6%; 95% CI:39.9 to 80.5%), and oesophageal cancer (51.5%; 95% CI:39.9 to 62.0%). For each risk factor studied across genders, tobacco smoking contributed the most (14.3%; 95% CI:9.9 to 17.3%), followed by excess weight (7.0%; 95% CI:4.1 to 10.2%), physical inactivity (1.0%; 95% CI:0.4 to 1.7%) and alcohol intake (0.6%; 95% CI:0.2 to 1.0%).
conclusionFindings from this study suggests that tobacco smoking and excess weight are the two predominant factors out of the four studied risk factors for cancer cases in Malaysia. Nationwide public health prevention campaigns tailored to these risk factors are recommended. However, the other risk factors such as physical inactivity and alcohol intake shall not be neglected. PAFs are estimated based on the best available data that we have currently. Regular collection of other risk factor exposure prevalence data is vital for future analyses.
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