Evidence map›Paper›PMID 33636169›Full record

ArticleBiophysical journal2021

Probing E. coli SSB protein-DNA topology by reversing DNA backbone polarity.

Alexander G Kozlov, Timothy M Lohman

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular insights into the prototypical single-stranded DNA-binding protein fromCritical reviews in biochemistry and molecular biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander G KozlovDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Timothy M LohmanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis, St. Louis, Missouri. Electronic address: lohman@wustl.edu.
Washington University in St. Louis · US

Funding

SSB PROTEIN/DNA INTERACTIONSR01GM030498 · NIGMS · WASHINGTON UNIVERSITY · PI LOHMAN, TIMOTHY M · 1985 to 2019
$7.4M
Mechanisms of Helicases, Translocases and SSB Proteins involved in Genome MaintenanceR35GM136632 · NIGMS · WASHINGTON UNIVERSITY · PI Timothy M Lohman · 2020 to 2026
$5.5M
NIGMS NIH HHS R01 GM030498NIGMS NIH HHS R35 GM136632
6 · The paper itself

Abstract

Escherichia coli single-strand (ss) DNA binding protein (SSB) is an essential protein that binds ssDNA intermediates formed during genome maintenance. SSB homotetramers bind ssDNA in two major modes, differing in occluded site size and cooperativity. The (SSB)

Indexed as

Escherichia coliEscherichia coli ProteinsDNA-Binding ProteinsDNA ProbesDNA, Single-StrandedProtein BindingDNA-Binding ProteinsDNA ProbesDNA, Single-StrandedEscherichia coli ProteinsSSB protein, E coli

Identifiers

PMID33636169
PMCPMC8105733
OpenAlexW3131639630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.