Evidence map›Paper›PMID 33636131›Full record

ArticleCell2021

Bone resorption goes green.

Jameel Iqbal, Mone Zaidi

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Developmental Pathways of Immature CD11cInternational journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jameel IqbalMount Sinai Bone Program, Center for Translational Medicine and Pharmacology, Department of Medicine and of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, James J. Peters VA Medical Center, Bronx, NY 10463, USA.
Mone ZaidiMount Sinai Bone Program, Center for Translational Medicine and Pharmacology, Department of Medicine and of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: mone.zaidi@mssm.edu.
Icahn School of Medicine at Mount Sinai · USMount Sinai Medical Center · US

Funding

Role of FSH in Osreoclast Formation and FunctionR01AG023176 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI ZAIDI, MONE · 2003 to 2012
$4.4M
NIA NIH HHS R01 AG023176
6 · The paper itself

Abstract

In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed "osteopmorhs," which re-form into osteoclasts at distal bone sites (McDonald et al., 2021). These findings overturn the long-standing premise that osteoclasts differentiate solely from hematopoietic precursors and undergo apoptosis after completing resorption.

Indexed as

Bone ResorptionBone and BonesHumansOsteoclasts

Identifiers

PMID33636131
PMCPMC11658024
OpenAlexW3129526799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.